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Estrogenicity Of Soy Formula

Estrogenicity Of Soy Formula
大豆配方奶粉的雌激素作用
批准号：
8553695
负责人：
WALTER ROGAN
金额：
$53.41万
依托单位：
NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8553695
关键词：
2 year oldBehaviorBone DensityBone GrowthBreastBreast FeedingCattleChildEstradiolEstrogensEvaluationGenisteinGonadal Steroid HormonesGonadotropinsGrowth and Development functionInfantIsoflavonesLanguage DevelopmentLongitudinal StudiesMethodsMilkModelingOrganOvaryPlaySerumSoybeansTissuesUterusdaidzeinfeedingsoy

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中文摘要
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英文摘要
Genistein and daidzein are estrogenic isoflavones found in soybeans. Although they are much less potent than estradiol, infants fed soy formula have serum concentrations that are up to 4 orders of magnitude higher than estradiol. We have been in the field with a longitudinal study of infants up to 9 months old, looking in detail at the growth and development of their estrogen-responsive tissue as well as sex hormones and gonadotropins. We have developed methods for studying play behavior, bone density, and language acquisition in 1 and 2 year olds, and completed a pilot recruitment evaluation. For all these studies, the exposed group are children using soy formula, compared with breast fed or cow milk formula.
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