Research Training in Veterinary & Comparative Pathology

描述（由申请人提供）：哈佛医学院（HMS）的兽医和比较病理学研究培训计划旨在为兽医从事生物医学研究做好准备，重点是实验病理学和使用非人类灵长类动物（NHP）模型研究人类疾病的发病机制和治疗。这项培训资助以新英格兰灵长类动物研究中心（NEPRC）为中心，包括HMS的其他组成部分和其他地区机构的参与。所有学员均为博士后水平，并被任命为HMS病理学系研究员。该培训计划旨在遵循为期一年的国家发改委资助的解剖病理学强化培训。在被任命为NCRR T32项目后，学员将接受使用NHP模型设计和实施实验的指导，在NIH拨款申请和同行评审过程的准备方面获得指导，并广泛接触实验病理学中使用的最先进的调查工具和当代研究方法，包括免疫组织化学，免疫电子显微镜，原位杂交，流式细胞术，共聚焦显微镜，激光捕获显微解剖，聚合酶链反应和分子生物学。培训计划将包括HMS和哈佛大学公共卫生学院的正式课程，参加NEPRC的研究会议和研讨会，参加国家和地区病理学和科学会议，并在一名既定调查员的监督下完成一项研究项目，并在同行评审的期刊上发表论文。攻读研究生学位的学员可以申请在此培训补助金支持下进行的研究项目，以满足哈佛大学或马萨诸塞大学医学院研究生课程的博士学位要求。因此，这项综合培训计划将整合NEPRC的独特资源，哈佛医学院及其附属机构的优秀研究环境，建立一个研究人员的领域，以实现为合格的兽医提供必要的研究培训和经验的长期目标，使他们能够成功地竞争研究经费，因为他们准备作为实验病理学家和研究科学家的学术生涯。

DESCRIPTION (provided by applicant): The Research Training Program in Veterinary and Comparative Pathology at Harvard Medical School (HMS) is designed to prepare veterinarians for careers in biomedical research, with an emphasis on training in experimental pathology and in the use of nonhuman primate (NHP) models to study the pathogenesis and treatment of human diseases. This training grant is centered at the New England Primate Research Center (NEPRC) and includes the participation of other components of HMS and other area institutions. All trainees are at the postdoctoral level and are appointed as Research Fellows in the Department of Pathology of HMS. The training program is designed to follow a one year, NEPRC-funded period of intensive training in anatomical pathology. After appointment to the NCRR T32 program, trainees receive instruction in the design and implementation of experiments using NHP models, mentoring in the preparation of NIH grant applications and the peer review process, and broad exposure to state-of-the-art investigative tools and contemporary research methods used in experimental pathology, including immunohistochemistry, immunoelectron microscopy, in situ hybridization, flow cytometry, confocal microscopy, laser capture microdissection, PCR, and molecular biology. The training program will include formal coursework at HMS and the Harvard School of Public Health, participation in research conferences and seminars at the NEPRC, attendance at national and regional pathology and scientific meetings, and the completion of a research project under the supervision of an established investigator that results in the publication of manuscripts in peer-reviewed journals. Trainees pursuing a graduate degree may apply the research projects performed while supported by this training grant towards the fulfillment of the requirements of a PhD in graduate programs at Harvard University or the University of Massachusetts Medical School. Thus, this comprehensive training program will integrate the unique resources of the NEPRC, the outstanding research environment of Harvard Medical School and its affiliated institutions, and a field of established investigators to accomplish the long-term objective of providing qualified veterinarians with the requisite research training and experience to enable them to successfully compete for research funding as they prepare for academic careers as experimental pathologists and research scientists.