Interferon mediated control of Legionella infection
Interferon mediated control of Legionella infection
批准号:
nhmrc : 1145244
负责人:
Prof Elizabeth Hartland
金额:
$42.52万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2020-12-31
中文摘要
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英文摘要
Bacterial lung infections are a serious cause of illness and death in humans. To fight infection the body activates the immune system using a network of signalling molecules. We are studying exactly how one of these signalling molecules called interferon controls the infection. Interferon induces the killing of bacteria that are replicating inside human lung cells. How interferon drives bacterial death is not known and this will be studied in this proposal.
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Interferon mediated control of Legionella infection
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批准号:nhmrc : GNT1145244
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项目类别:Project Grants
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资助金额:$62.88万
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财政年份:2018
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负责人:Prof Elizabeth Hartland
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依托单位:
Nucleomodulin effectors of the environmental pathogen Legionella
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批准号:DP180102725
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项目类别:Discovery Projects
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资助金额:$28.97万
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财政年份:2018
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负责人:Prof Elizabeth Hartland
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依托单位:
Glycosyltransferase effectors from bacterial enteric pathogens
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批准号:nhmrc : GNT1098826
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项目类别:Project Grants
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资助金额:$77.26万
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财政年份:2016
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负责人:Prof Elizabeth Hartland
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依托单位:
Glycosyltransferase effectors from bacterial enteric pathogens
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批准号:nhmrc : 1098826
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项目类别:Project Grants
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资助金额:$53.15万
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财政年份:2016
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负责人:Prof Elizabeth Hartland
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依托单位:
Novel bacterial cysteine proteases targeting innate immunity
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批准号:nhmrc : 1100609
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项目类别:Project Grants
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资助金额:$54.86万
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财政年份:2016
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负责人:Prof Elizabeth Hartland
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依托单位:
Ubiquitination in Legionella infection
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批准号:nhmrc : GNT1098820
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项目类别:Project Grants
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资助金额:$50.15万
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财政年份:2016
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负责人:Prof Elizabeth Hartland
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依托单位:
Ubiquitination in Legionella infection
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批准号:nhmrc : 1098820
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项目类别:Project Grants
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资助金额:$34.37万
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财政年份:2016
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负责人:Prof Elizabeth Hartland
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依托单位:
Novel bacterial cysteine proteases targeting innate immunity
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批准号:nhmrc : GNT1100609
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项目类别:Project Grants
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资助金额:$79.76万
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财政年份:2016
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负责人:Prof Elizabeth Hartland
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依托单位:
Death receptor signaling during E. coli and Salmonella infection
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批准号:nhmrc : 1044061
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项目类别:Project Grants
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资助金额:$39.08万
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财政年份:2013
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负责人:Prof Elizabeth Hartland
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依托单位:
Biology and evolution of intracellular parasitism
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批准号:DP130102689
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项目类别:Discovery Projects
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资助金额:$30.31万
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财政年份:2013
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负责人:Prof Elizabeth Hartland
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依托单位:
The biology, structure and function of bacterial virulence effectors
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批准号:FT0990267
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项目类别:ARC Future Fellowships
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资助金额:$56.26万
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财政年份:2010
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负责人:Prof Elizabeth Hartland
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依托单位:
The intracellular replicative niche of Legionella species and Coxiella burnetii.
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批准号:nhmrc : 566568
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项目类别:NHMRC Project Grants
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资助金额:$35.32万
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财政年份:2009
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负责人:Prof Elizabeth Hartland
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依托单位:
Contribution of nuclear targeting of the NleE-OspZ family of proteins to Escherichia coli and Shigella virulence
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批准号:nhmrc : 566639
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项目类别:NHMRC Project Grants
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资助金额:$36.17万
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财政年份:2009
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负责人:Prof Elizabeth Hartland
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依托单位:
Host cell targets of bacterial virulence effectors
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批准号:DP0773921
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项目类别:Discovery Projects
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资助金额:$18.25万
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财政年份:2008
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负责人:Prof Elizabeth Hartland
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依托单位:
The host specificity of bacterial pathogens
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批准号:DP0451154
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项目类别:Discovery Projects
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资助金额:$15.67万
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财政年份:2004
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负责人:Prof Elizabeth Hartland
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依托单位:
Identification and characterisation of novel virulence genes in attaching and effacing strains of Escherichia coli
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批准号:nhmrc : 216709
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项目类别:NHMRC Project Grants
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资助金额:$18.76万
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财政年份:2002
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负责人:Prof Elizabeth Hartland
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依托单位:
Characterisation of enterohaemorrhagic Escherichia coli lacking classical virulence markers
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批准号:nhmrc : 194235
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项目类别:NHMRC Project Grants
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资助金额:$9.38万
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财政年份:2002
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负责人:Prof Elizabeth Hartland
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依托单位:
Pathogenesis of infections with enteropathogenic and enterohemorrhagic Escherichia coli
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批准号:nhmrc : 7202
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项目类别:Early Career Fellowships
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资助金额:$3.67万
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财政年份:2000
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负责人:Prof Elizabeth Hartland
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依托单位:
国内基金
海外基金
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