Consolidated Basic Cancer Research Program

综合基础癌症研究计划

• 批准号: 8894146
• 负责人: Dario C Altieri
• 金额: $ 9.26万
• 依托单位: WISTAR INSTITUTE
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-04-01 至 2019-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8894146
• 关键词: Agreement; Area; Basic Cancer Research; Budgets; Cancer Biology; Cancer Center; Cancer Research Project; Collaborations; Decision Making; Development; Education; Environment; Faculty; Funding; Growth; Health system; Malignant Neoplasms; Malignant neoplasm of ovary; Mentors; Mission; National Cancer Institute; Patients; Process; Publications; Recruitment Activity; Research; Research Infrastructure; Resource Sharing; Schedule; Scientist; Specimen; Strategic Planning; The Wistar Institute; Training; Vision; anticancer research; base; cancer research center director; career development; melanoma; member; multidisciplinary; next generation; patient oriented; programs; tool

DESCRIPTION (provided by applicant): The Wistar Institute Cancer Center has undergone transformative changes during the last budget period that reconfigured every administrative, scientific and educational segment of the organization. Coinciding with the recruitment of Dr. Altieri as the first, dedicated Director of the Cancer Center, an inclusive, transparent and highly consultative strategic planning process was completed in the last budget period. Emerging from the 2012 Cancer Center Strategic Plan was a unifying vision to conquer cancer through outstanding research, education and partnership and an underlying mission to merge basic, translational and patient-oriented cancer research in a single scientific continuum. The stepwise but decisive implementation of the new strategic directives during the last budget period established a new administrative and decision-making infrastructure of the Cancer Center, comprehensively realigned scientific Programs for optimal research impact and synergistic collaboration, and reorganized Shared Resources as financially-sustainable engines of Wistar discoveries. To enable the vision of the Cancer Center in translational and patient-oriented cancer research, multidisciplinary, inter-programmatic initiatives were launched in the areas of melanoma and ovarian cancer, and unique inter-institutional agreements were established with regional health systems for access to clinically-annotated, primary patient specimens. Training the next generation of cancer scientists became a strategic priority, fulfilled with the launch of new, Wistar-based graduate program in cancer biology and the deployment of expansive mentoring and career development tools for junior faculty. Against this backdrop, the Cancer Center successfully recruited nine new faculty members at all academic ranks, many of them research leaders, during the last budget cycle, grew its National Cancer Institute (NCI) funding base by 21% from $8.1 million in 2008 to $10.2 million in 2013, and expanded its collaborative publications from an average of 9.7% in 2008 to 29.3% in 2013 across all three scientific Programs. The extraordinary growth of the past budget period, increased cancer focus, refinement of scientific themes and highly collaborative environment have now placed the Cancer Center on a steep upward trajectory, ideally suited to leverage the opening of a new, $102 million, seven story tall, Wistar Research Tower scheduled for the summer of 2014. Providing for the largest faculty and facility expansion of Wistar in forty years, the new Tower will enable the further development of focused and multidisciplinary flagship research themes in each Program along the continuum of basic, translational and patient-oriented cancer research.

描述（由申请人提供）：Wistar研究所癌症中心在上一个预算期间经历了变革，重新配置了该组织的每一个行政，科学和教育部门。与Altieri博士作为癌症中心的第一位专职主任的招聘相吻合，这是一个包容，透明和高度开放的中心。 在上一个预算期间完成了协商战略规划进程。从2012年癌症中心战略计划中出现的是一个统一的愿景，即通过杰出的研究，教育和伙伴关系征服癌症，以及将基础，转化和以患者为导向的癌症研究合并为一个单一的科学连续体的基本使命。在上一个预算期内，新战略指令的逐步但果断的实施建立了癌症中心新的行政和决策基础设施，全面重新调整了科学计划，以实现最佳研究影响和协同合作，并重组了共享资源，使其成为Wistar发现的财务可持续引擎。为了实现癌症中心在转化和以患者为导向的癌症研究方面的愿景，在黑色素瘤和卵巢癌领域启动了多学科，跨计划的举措，并与区域卫生系统建立了独特的机构间协议，以获得临床注释的主要患者标本。培训下一代癌症科学家成为一个战略重点，随着新的，基于Wistar的癌症生物学研究生课程的推出，以及为初级教师部署广泛的指导和职业发展工具，实现了这一目标。在这种背景下，癌症中心成功地招募了9名新的教职员工在所有学术级别，其中许多人是研究领导者，在上一个预算周期，增加了21%的国家癌症研究所（NCI）的资金基础从2008年的810万美元到2013年的1020万美元，在所有三个科学计划中，合作出版物的平均比例从2008年的9.7%增加到2013年的29.3%。在过去的预算期间，增加癌症的关注，科学主题的细化和高度合作的环境的非凡增长，现在已经把癌症中心放在一个陡峭的上升轨迹，非常适合利用一个新的，1.02亿美元，七层楼高，Wistar研究塔定于2014年夏天开幕。为提供最大的教师和设施扩建的Wistar在四十年来，新塔将使重点和多学科的旗舰研究主题的进一步发展，在每个程序沿着连续的基础，转化和以患者为导向的癌症研究。