Back pain Outcomes using Longitudinal Data- Extension of Research (BOLDER)

使用纵向数据的背痛结果 - 研究扩展 (BOLDER)

• 批准号: 8692115
• 负责人: JEFFREY G JARVIK
• 金额: $ 74.07万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-30 至 2016-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8692115
• 关键词: Back; pain; Outcomes; using; Longitudinal

DESCRIPTION (provided by applicant): Low back pain is an Institute of Medicine priority condition for comparative effectiveness research and it remains a particularly important problem for the elderly, an AHRQ priority population. Nearly one-third of the population over age 65 has severe low back pain and it is one of the most common reasons for physician visits. There is a paucity of evidence-based guidelines for the elderly, who have a different distribution of causal conditions than younger populations. Important questions remain unanswered regarding the comparative effectiveness of most commonly used diagnostic tests and treatments. Funded by a $10 million AHRQ/ARRA grant, we have enrolled a large inception cohort of senior patient with low back pain from three geographically and racially diverse HMOs: Kaiser Northern California, Henry Ford Health System and Harvard Vanguard/Harvard Pilgrim. Patients who enroll in the registry complete validated, standardized measures of pain, back-related disability, and health-related quality of life at enrollment and at regular follow-up intervals. The overall gol of our project, the Back pain Outcomes using Longitudinal Data- Extension of Research (BOLDER), is to extend the usefulness and improve the capabilities of the BOLD cohort infrastructure. Using a stakeholder engagement process, we will enhance the current data infrastructure to address stakeholder-relevant questions. Stakeholder engagement will include health system and payer stakeholders at the various sites as well as senior patients with back pain. Specifically, we will extend our existing data infrastructure by collecting longer-term patiet reported outcomes (PRO) and electronic medical record data collected from diverse data systems within and between health systems. We will use stakeholder input to focus our additional data collection on data that will be of greatest value to stakeholders and can address important questions regarding the long-term clinical effectiveness of back pain diagnostic and treatment interventions.

描述（由申请人提供）：腰痛是比较有效性研究的医学研究所优先条件，它仍然是老年人的一个特别重要的问题，AHRQ优先人群。近三分之一的65岁以上的人口患有严重的腰痛，这是医生就诊的最常见原因之一。老年人缺乏循证指南，他们的因果关系分布与年轻人不同。关于最常用的诊断测试和治疗的比较有效性的重要问题仍然没有答案。由1000万美元的AHRQ/ARRA拨款资助，我们已经招募了一个大型的老年患者下背痛的初始队列从三个地理和种族多样化的健康维护组织：凯撒北方加州，亨利福特卫生系统和哈佛先锋/哈佛朝圣者。登记入组的患者在入组时和定期随访时完成疼痛、背部相关残疾和健康相关生活质量的经验证的标准化测量。我们项目的总体目标，使用纵向数据的背痛结局-研究扩展（BOLDER），是扩展BOLD队列基础设施的有用性和提高其能力。通过利益相关者参与流程，我们将加强当前的数据基础设施，以解决与利益相关者相关的问题。利益相关者的参与将包括各站点的卫生系统和付款人利益相关者以及患有背痛的老年患者。具体而言，我们将通过收集从卫生系统内部和之间的不同数据系统收集的长期患者报告结果（PRO）和电子病历数据来扩展我们现有的数据基础设施。我们将利用利益相关者的意见，将我们额外的数据收集集中在对利益相关者最有价值的数据上，并可以解决有关背痛诊断和治疗干预措施的长期临床有效性的重要问题。

项目成果

Performance of the Functional Comorbidity Index (FCI) in Prognostic Models for Risk Adjustment in Patients With Back Pain.

功能性合并症指数 (FCI) 在背痛患者风险调整的预后模型中的表现。

• DOI: 10.1002/pmrj.12315
• 发表时间: 2020
• 期刊: PM & R : the journal of injury, function, and rehabilitation
• 作者: Rundell,SeanD;Resnik,Linda;Heagerty,PatrickJ;Kumar,Amit;Jarvik,JeffreyG
• 通讯作者: Jarvik,JeffreyG

Associations Between Relative Value Units and Patient-Reported Back Pain and Disability.

相对价值单位与患者报告的背痛和残疾之间的关联。

• DOI: 10.1177/2333721416686019
• 发表时间: 2017
• 期刊: Gerontology & geriatric medicine
• 影响因子: 2.7
• 作者: Gold,LauraS;Bryan,Matthew;Comstock,BryanA;Bresnahan,BrianW;Deyo,RichardA;Nedeljkovic,SrdjanS;Nerenz,DavidR;Heagerty,Patrick;Jarvik,JeffreyG
• 通讯作者: Jarvik,JeffreyG

Multi-site Pain Is Associated with Long-term Patient-Reported Outcomes in Older Adults with Persistent Back Pain.

多部位疼痛与持续性背痛老年人的长期患者报告结果相关。

• DOI: 10.1093/pm/pny270
• 发表时间: 2019
• 期刊: Pain medicine (Malden, Mass.)
• 作者: Rundell,SeanD;Patel,KushangV;Krook,MelissaA;Heagerty,PatrickJ;Suri,Pradeep;Friedly,JannaL;Turner,JudithA;Deyo,RichardA;Bauer,Zoya;Nerenz,DavidR;Avins,AndrewL;Nedeljkovic,SrdjanS;Jarvik,JeffreyG
• 通讯作者: Jarvik,JeffreyG