Production , purification and preparation of various candidiate vaccines
Production , purification and preparation of various candidiate vaccines
批准号:
8741643
负责人:
Joseph Shiloach
金额:
$28.59万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
Bacillus anthracisBioreactorsBiotechnologyBioterrorismCell Culture TechniquesCellsChimeric ProteinsCollaborationsConjugate VaccinesDevelopmentE coli polysaccharide K1Haemophilus influenzaeInfluenzaLaboratoriesMDCK cellMalariaMethodsNational Institute of Allergy and Infectious DiseaseNational Institute of Child Health and Human DevelopmentPertussisPreparationProductionProteinsPublic HealthRespiratory syncytial virusRotavirusRotavirus VaccinesScientistShigellaShigella flexneriStructureSuspension substanceSuspensionsVaccinesViral VaccinesWorkimprovedinfluenza virus vaccineresearch studytransmission process
中文摘要
生物技术实验室正在结束其与NICHD和NIAID的合作工作,开发针对福氏志贺氏菌、索尼志贺菌、百日咳、甲型流感嗜血杆菌、百日咳的新型结合疫苗,以及炭疽芽孢杆菌蛋白疫苗和疟疾传播阻断疫苗。
英文摘要
The Biotechnology Lab is wrapping its collaboration work with the NICHD and NIAID on the development of new conjugated vaccines against Shigella flexneri, Shigella Sonnie, Bortedella pertussis Haemophilus influenzae type A, Bortedella pertussis, and protein vaccines for Bacillus anthracis and Malaria transmission blocking vaccine.
Working together with scientists from the FDA, the laboratory is evaluating the potential production of influenza virus vaccine form the newly developed MDCK cells, and on the structure of the polysaccharide from E. coli K1 and Meningococcal C. The Biotechnology Lab continued to work on the development of new production approaches for viral vaccines by using suspension cell culture, concentrating on influenza and rotavirus. In addition we are working on expressing the respiratory syncytial Virus (RSV) fusion protein from HEK cells growing in suspension in bioreactor. The proper constructs are being made and preliminary experiments on expression and purifications are being conducted.
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Large-scale production and purification of biological compounds
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批准号:9356265
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项目类别:
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资助金额:$57.8万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
Identification of genes related to spcific properties of mammalian cells
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批准号:10697827
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项目类别:
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资助金额:$13.7万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
Large-scale Production & Purification Of Compounds With
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批准号:6673344
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
Large-scale production and purification of biological compounds
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批准号:7593413
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项目类别:
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资助金额:$30.26万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
Identification of genes related to spcific properties of mammalian cells
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批准号:10250250
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项目类别:
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资助金额:$56.1万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
Large-scale production and purification of biological compounds
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批准号:9148972
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项目类别:
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资助金额:$59.58万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
Large-scale Production & Purification Of Compounds With
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批准号:6983602
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
Large-scale Production & Purification Of Compounds With
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批准号:6503224
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
Large-scale production and purification of biological compounds
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批准号:8554134
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项目类别:
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资助金额:$63.12万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
Identification of genes realted to spcific properties of mammlian cells
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批准号:7967773
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项目类别:
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资助金额:$32.36万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
Large-scale Production & Purification Of Compounds With
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批准号:7334670
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
Identification of genes related to spcific properties of mammalian cells
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批准号:8553669
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项目类别:
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资助金额:$31.56万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
Understanding metabolism and stress conditions of recombinant E. coli
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批准号:8553670
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项目类别:
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资助金额:$31.56万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
Production , purification and preparation of various candidiate vaccines
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批准号:9148975
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项目类别:
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资助金额:$31.38万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
Identification of genes realted to spcific properties of mammlian cells
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批准号:7734322
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项目类别:
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资助金额:$26.55万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
Understanding metabolism and stress conditions of recombinant E. coli
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批准号:8939723
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项目类别:
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资助金额:$16.69万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
Production , purification and preparation of various candidiate vaccines
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批准号:7593790
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项目类别:
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资助金额:$30.26万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
Production and purification of biological compounds
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批准号:10250260
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项目类别:
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资助金额:$71.68万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
LARGE-SCALE PRODUCTION & PURIFICATION OF COMPOUNDS WITH BIOLOGICAL ACTIVITY
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批准号:6289715
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
LARGE-SCALE PRODUCTION & PURIFICATION OF COMPOUNDS WITH BIOLOGICAL ACTIVITY
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批准号:6432056
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:Joseph Shiloach
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依托单位:
海外基金