Conduct of studies to evaluate the toxicity and carcinogenicity of multiwalled carbon nanotubes in laboratory animals for the National Toxicology Program (NTP)

为国家毒理学计划（NTP）开展研究，评估多壁碳纳米管对实验动物的毒性和致癌性

• 批准号: 9471290
• 负责人: BARNEY SPARROW
• 金额: $ 123.77万
• 依托单位: BATTELLE MEMORIAL INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-15 至 2018-04-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9471290
• 关键词: Animals; Autopsy; Breathing; Carbon Nanotubes; Chemicals; Chronic; Evaluation; Goals; Human; Industrialization; Laboratory Animals; Life; Nanotechnology; National Toxicology Program; Phase; Risk; Toxic effect; Toxicity Tests; carcinogenicity; hazard; immunotoxicity

The goal of this project is to characterize the chronic toxicity and carcinogenicity of multiwalled carbon nanotubes (MWCNT). MWCNT have a wide variety of industrial applications and the use is increasing rapidly. Two-year studies, which include prechronic interim necropsies and immunotoxicity evaluations are in the in life phase. Keywords: toxicity, carcinogenicity, inhalation, multiwalled carbon nanotubes, nanotechnology

本项目旨在研究多壁碳纳米管（MWCNT）的慢性毒性和致癌性。纳米碳纳米管具有广泛的工业应用，其用途正在迅速增加。为期两年的研究，包括慢性前中期尸检和免疫毒性评估，处于生命阶段。