The Vanderbilt Emergency Care Research Training Program

H.项目概要/摘要 在理解急性、危及生命的疾病的病理生理学方面取得了显著进展， 发生在过去的几十年里。然而，能够翻译这些的临床研究者太少了。 研究发现，以改善护理，使其至关重要的是建立和维持一个骨干的紧急护理 临床科学家需要创新的方案来识别、培训和支持这些人。Vanderbilt 在发展临床科学家的职业生涯方面有着极其成功的历史。一个这样的程序是 范德比尔特急诊医学研究培训计划，2011年资助的K12计划， 紧急护理的临床科学家。在该计划的7名学者中，有3名成功获得了外部 2015年，有3个国家正在审查或准备K23申请。针对RFA-HL-16- 019，我们建议通过以下方式扩展我们成功的K12计划：1）专门的高级指导 团队; 2）多样化的学者名册; 3）医学，急诊和其他部门之间的密切合作 医学，精神病学和护理学院，都位于一个单一的校园; 4）一个环境， 非常成功的临床科学家培训和职业发展的丰富历史; 5）强大的基础设施， 临床和转化研究;以及6）强大的机构支持。我们建议共招聘6名 临床医生-已完成住院医师（或具有博士学位或同等培训的人员）并显示 成功追求学术研究事业的特殊才能。该计划将集中于 发展3个核心领域的专业知识：急性心肺急症，急性 精神疾病和以病人为中心的急诊护理。项目总监艾伦B。马里兰州斯托罗 和医学博士托马斯J.王，已经在每个重点领域组建了一个专家团队，他们目前正在从事 成功的学术研究，并致力于培训和指导新的 investigators.早期职业（培训导师）和高级研究者（主要研究导师）将 联合收割机与职业发展专家（学术导师），以支持学者走向独立 从事紧急护理研究。

H. PROJECT SUMMARY/ABSTRACT Remarkable advances in understanding of the pathophysiology of acute, life-threatening disorders have occurred in the past several decades. However, there are too few clinical investigators who can translate these research findings into improved care, making it critical to create and maintain a cadre of emergency care clinician-scientists. Innovative programs are needed to identify, train, and support such individuals. Vanderbilt has an extremely successful history in developing the careers of clinician-scientists. One such program is the Vanderbilt Emergency Medicine Research Training Program, a K12 program funded in 2011 to develop clinician-scientists in emergency care. Of the 7 Scholars in this program, 3 have successfully obtained external K23 funding, and 3 have K23 applications under review or in preparation in 2015. In response to RFA-HL-16- 019, we propose to extend our successful K12 program by leveraging: 1) a dedicated and senior mentorship team; 2) a diverse Scholar roster; 3) strong collaboration between the Departments of Medicine, Emergency Medicine, and Psychiatry, and the School of Nursing, all located on a single campus; 4) an environment with a rich history of highly successful clinical-scientist training and career development; 5) a robust infrastructure for clinical and translational research; and 6) strong institutional support. We propose to recruit a total of 6 clinician-scientists who have completed residency (or those with PhDs or equivalent training) and who show exceptional aptitude for successfully pursuing an academic research career. The program will concentrate on developing expertise in 3 core areas: acute cardiopulmonary emergencies, the neurobiology of acute psychiatric illness, and patient-centered emergency nursing. The Program Directors, Alan B. Storrow, MD and Thomas J. Wang, MD, have assembled a team of experts in each focus area who are currently engaged in successful academic research and who have devoted their careers to training and mentoring new investigators. Both early-career (Mentors-in-Training) and senior investigators (Primary Research Mentors) will combine with experts in career development (Academic Mentors) to support the Scholars toward independent careers in emergency care research.