Neural and Cognitive Mechanisms for Removing Emotional Information from Working Memory
从工作记忆中删除情绪信息的神经和认知机制
基本信息
- 批准号:10689246
- 负责人:
- 金额:$ 75.52万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-08-23 至 2026-07-31
- 项目状态:未结题
- 来源:
- 关键词:AddressAffectAmygdaloid structureAnxietyAttentionBehaviorBrainBrain imagingCognitiveComputational TechniqueControl GroupsEffectivenessEmotionalExcisionFeedbackFunctional Magnetic Resonance ImagingGoalsIndividualIndividual DifferencesKnowledgeMachine LearningMeasuresMental DepressionMental ProcessesMental disordersMindNaturePatient Self-ReportPatternPersonsPrefrontal CortexProcessPsyche structurePsychopathologyRecording of previous eventsRecurrenceReportingResearchResearch PersonnelScientistSensorySeriesShort-Term MemoryStimulusSymptomsSystemTechniquesTestingThinkingTimeTrainingUpdateVehicle crashVisual CortexWorkassociated symptombasecognitive controlcomputer sciencedesignexpectationimaging approachimprovedindexinginnovationinsightneuralneural patterningneurofeedbackneuroimagingneuromechanismnoveloperationruminationsuccessthought controlweapons
项目摘要
PROJECT SUMMARY
The overall objective of the current project is to understand how emotional thoughts can be removed from one's
mind. Most psychiatric disorders are characterized by an inability to remove negative, intrusive, and maladaptive
thoughts from mind. Previously examining whether an individual has purged a thought from mind has relied
mainly on self-report measures (e.g., “Yes, I stopped thinking about the car crash”). In the proposed research,
the research team will use a combination of brain imaging approaches with machine learning techniques drawn
from computer science to provide an objective neural marker of whether indeed a thought has been removed
from mind. This approach builds on proven success with this technique pioneered by the research team. This
prior work focused on the removal of (emotionally neutral) information from mind and demonstrated that
suppressing a specific thought and clearing one's mind of all thought rely on different neural mechanisms.
Moreover, the prior findings indicated that these mental operations differentially affect one's ability to take in
new information after the old information has been removed. The focus of the proposed project will be to
examine how emotional information is removed from current thought. The project will ask three main questions.
First, it will examine whether the emotional valence of information affects the engagement and effectiveness of
neural systems involved in removing information from mind. A series of parallel studies, one involving
neuroimaging and the other examining people's behavior, are designed to examine whether these removal
operations are affected by a) the emotional valence (positive, negative) of the information to be removed, b) the
emotional valence of the information that should now be brought to mind and c) the match (e.g., positive,
positive) or mismatch (positive, negative) between the valence of the information being removed and that which
replaces it. Expectations are that negative information will be harder to remove and easier to be brought into
current thought than positive information. Second, the project will examine whether the effectiveness of these
removal operations varies across individuals. It will assess the degree to which individuals report that they have
difficulty controlling their thoughts, the degree to which they have symptoms related to depression and anxiety,
and their ability to hold and manipulate information in working memory. Expectations are that individuals who
report difficulty in controlling their thoughts will have difficulty in removing information from mind, and that
people with higher levels of depression will have specific difficulties in removing negative thoughts. Third, the
project will examine whether individuals can be trained, using real-time feedback about brain function during
neuroimaging, to effectively remove thoughts from mind by providing them with a sense of what it feels like to
successfully remove a thought. The results of the proposed project will have important implications both for
understanding the recurrent and intrusive thoughts that characterize psychopathology and for providing
insights on how they might be reduced.
项目总结
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Marie T Banich其他文献
Marie T Banich的其他文献
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{{ truncateString('Marie T Banich', 18)}}的其他基金
Functional and Anatomical investigations of Domain-specific and Domain-General Alterations in Neural Systems underlying Math & Reading Difficulty
数学基础神经系统中特定领域和通用领域改变的功能和解剖学研究
- 批准号:
10686619 - 财政年份:2022
- 资助金额:
$ 75.52万 - 项目类别:
Neural and Cognitive Mechanisms for Removing Emotional Information from Working Memory
从工作记忆中删除情绪信息的神经和认知机制
- 批准号:
10522600 - 财政年份:2022
- 资助金额:
$ 75.52万 - 项目类别:
Removing and Manipulating Emotional Information in Working Memory: Cognitive and Neural Representations
删除和操纵工作记忆中的情感信息:认知和神经表征
- 批准号:
10450323 - 财政年份:2021
- 资助金额:
$ 75.52万 - 项目类别:
14/21 ABCD-USA Consortium: Research Project Site at CU Boulder
14/21 ABCD-美国联盟:科罗拉多大学博尔德分校研究项目现场
- 批准号:
10376202 - 财政年份:2020
- 资助金额:
$ 75.52万 - 项目类别:
14/21 ABCD-USA Consortium: Research Project Site at CU Boulder
14/21 ABCD-美国联盟:科罗拉多大学博尔德分校研究项目现场
- 批准号:
9981394 - 财政年份:2020
- 资助金额:
$ 75.52万 - 项目类别:
14/21 ABCD-USA Consortium: Research Project Site at CU Boulder
14/21 ABCD-美国联盟:科罗拉多大学博尔德分校研究项目现场
- 批准号:
10598049 - 财政年份:2020
- 资助金额:
$ 75.52万 - 项目类别:
Clearing the Contents of Working Memory: Mechanisms and Representations
清除工作记忆的内容:机制和表征
- 批准号:
9301668 - 财政年份:2016
- 资助金额:
$ 75.52万 - 项目类别:
Prefrontal Mechanisms of Selection: Disrupted in Internalizing Psychopathology?
前额叶选择机制:内化精神病理学受到干扰?
- 批准号:
9273621 - 财政年份:2015
- 资助金额:
$ 75.52万 - 项目类别:
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