Neural and Cognitive Mechanisms for Removing Emotional Information from Working Memory

从工作记忆中删除情绪信息的神经和认知机制

基本信息

  • 批准号:
    10689246
  • 负责人:
  • 金额:
    $ 75.52万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2022
  • 资助国家:
    美国
  • 起止时间:
    2022-08-23 至 2026-07-31
  • 项目状态:
    未结题

项目摘要

PROJECT SUMMARY The overall objective of the current project is to understand how emotional thoughts can be removed from one's mind. Most psychiatric disorders are characterized by an inability to remove negative, intrusive, and maladaptive thoughts from mind. Previously examining whether an individual has purged a thought from mind has relied mainly on self-report measures (e.g., “Yes, I stopped thinking about the car crash”). In the proposed research, the research team will use a combination of brain imaging approaches with machine learning techniques drawn from computer science to provide an objective neural marker of whether indeed a thought has been removed from mind. This approach builds on proven success with this technique pioneered by the research team. This prior work focused on the removal of (emotionally neutral) information from mind and demonstrated that suppressing a specific thought and clearing one's mind of all thought rely on different neural mechanisms. Moreover, the prior findings indicated that these mental operations differentially affect one's ability to take in new information after the old information has been removed. The focus of the proposed project will be to examine how emotional information is removed from current thought. The project will ask three main questions. First, it will examine whether the emotional valence of information affects the engagement and effectiveness of neural systems involved in removing information from mind. A series of parallel studies, one involving neuroimaging and the other examining people's behavior, are designed to examine whether these removal operations are affected by a) the emotional valence (positive, negative) of the information to be removed, b) the emotional valence of the information that should now be brought to mind and c) the match (e.g., positive, positive) or mismatch (positive, negative) between the valence of the information being removed and that which replaces it. Expectations are that negative information will be harder to remove and easier to be brought into current thought than positive information. Second, the project will examine whether the effectiveness of these removal operations varies across individuals. It will assess the degree to which individuals report that they have difficulty controlling their thoughts, the degree to which they have symptoms related to depression and anxiety, and their ability to hold and manipulate information in working memory. Expectations are that individuals who report difficulty in controlling their thoughts will have difficulty in removing information from mind, and that people with higher levels of depression will have specific difficulties in removing negative thoughts. Third, the project will examine whether individuals can be trained, using real-time feedback about brain function during neuroimaging, to effectively remove thoughts from mind by providing them with a sense of what it feels like to successfully remove a thought. The results of the proposed project will have important implications both for understanding the recurrent and intrusive thoughts that characterize psychopathology and for providing insights on how they might be reduced.
项目概要 当前项目的总体目标是了解如何从一个人的情绪中消除情绪化想法。 头脑。大多数精神疾病的特点是无法消除消极的、侵入性的和适应不良的事物。 来自头脑的想法。之前检查一个人是否已经从头脑中清除了某种想法依赖于 主要是自我报告措施(例如,“是的,我不再考虑车祸”)。在拟议的研究中, 研究小组将结合使用大脑成像方法和机器学习技术来绘制 来自计算机科学,提供客观的神经标记,表明某个想法是否确实已被删除 从心里。这种方法建立在研究团队首创的这项技术已被证实的成功基础上。这 之前的工作重点是从头脑中删除(情感中立的)信息,并证明 抑制特定的想法和清除头脑中的所有想法依赖于不同的神经机制。 此外,先前的研究结果表明,这些心理操作会不同程度地影响一个人的吸收能力。 旧信息删除后新信息。拟议项目的重点是 检查情绪信息如何从当前思想中消除。该项目将提出三个主要问题。 首先,它将检查信息的情感效价是否影响信息的参与度和有效性。 涉及从头脑中删除信息的神经系统。一系列平行研究,其中一项涉及 神经影像学和其他检查人们行为的方法,旨在检查这些去除是否 操作受到以下因素的影响:a)要删除的信息的情绪价(正面,负面),b) 现在应该想到的信息的情感效价,以及 c) 匹配(例如,积极的、 被删除的信息的价数与被删除的信息的价数之间的不匹配(正、负)或不匹配(正、负) 取代它。预计负面信息将更难消除,更容易被带入 当前的想法多于积极的信息。其次,该项目将检验这些措施是否有效。 清除操作因人而异。它将评估个人报告他们拥有的程度 难以控制自己的想法,他们出现抑郁和焦虑症状的程度, 以及他们在工作记忆中保存和操纵信息的能力。期望是那些 报告称难以控制自己的思想,因此难以从头脑中消除信息,并且 抑郁程度较高的人在消除消极想法方面会遇到特定的困难。第三, 该项目将检查个人是否可以接受训练,使用有关大脑功能的实时反馈 神经影像学,通过向人们提供一种感觉,有效地从头脑中消除想法 成功去除一个念头。拟议项目的结果将对以下方面产生重要影响: 了解精神病理学特征的反复出现和侵入性想法,并提供 关于如何减少它们的见解。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Marie T Banich其他文献

Marie T Banich的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('Marie T Banich', 18)}}的其他基金

Functional and Anatomical investigations of Domain-specific and Domain-General Alterations in Neural Systems underlying Math & Reading Difficulty
数学基础神经系统中特定领域和通用领域改变的功能和解剖学研究
  • 批准号:
    10686619
  • 财政年份:
    2022
  • 资助金额:
    $ 75.52万
  • 项目类别:
Neural and Cognitive Mechanisms for Removing Emotional Information from Working Memory
从工作记忆中删除情绪信息的神经和认知机制
  • 批准号:
    10522600
  • 财政年份:
    2022
  • 资助金额:
    $ 75.52万
  • 项目类别:
Removing and Manipulating Emotional Information in Working Memory: Cognitive and Neural Representations
删除和操纵工作记忆中的情感信息:认知和神经表征
  • 批准号:
    10450323
  • 财政年份:
    2021
  • 资助金额:
    $ 75.52万
  • 项目类别:
14/21 ABCD-USA Consortium: Research Project Site at CU Boulder
14/21 ABCD-美国联盟:科罗拉多大学博尔德分校研究项目现场
  • 批准号:
    10376202
  • 财政年份:
    2020
  • 资助金额:
    $ 75.52万
  • 项目类别:
14/21 ABCD-USA Consortium: Research Project Site at CU Boulder
14/21 ABCD-美国联盟:科罗拉多大学博尔德分校研究项目现场
  • 批准号:
    9981394
  • 财政年份:
    2020
  • 资助金额:
    $ 75.52万
  • 项目类别:
14/21 ABCD-USA Consortium: Research Project Site at CU Boulder
14/21 ABCD-美国联盟:科罗拉多大学博尔德分校研究项目现场
  • 批准号:
    10598049
  • 财政年份:
    2020
  • 资助金额:
    $ 75.52万
  • 项目类别:
Clearing the Contents of Working Memory: Mechanisms and Representations
清除工作记忆的内容:机制和表征
  • 批准号:
    9301668
  • 财政年份:
    2016
  • 资助金额:
    $ 75.52万
  • 项目类别:
ABCD-USA Consortium: Twin Research Project
ABCD-美国联盟:双胞胎研究项目
  • 批准号:
    9150609
  • 财政年份:
    2015
  • 资助金额:
    $ 75.52万
  • 项目类别:
Prefrontal Mechanisms of Selection: Disrupted in Internalizing Psychopathology?
前额叶选择机制:内化精神病理学受到干扰?
  • 批准号:
    9273621
  • 财政年份:
    2015
  • 资助金额:
    $ 75.52万
  • 项目类别:
ABCD-USA Consortium: Twin Research Project
ABCD-美国联盟:双胞胎研究项目
  • 批准号:
    9054255
  • 财政年份:
    2015
  • 资助金额:
    $ 75.52万
  • 项目类别:

相似海外基金

How Does Particle Material Properties Insoluble and Partially Soluble Affect Sensory Perception Of Fat based Products
不溶性和部分可溶的颗粒材料特性如何影响脂肪基产品的感官知觉
  • 批准号:
    BB/Z514391/1
  • 财政年份:
    2024
  • 资助金额:
    $ 75.52万
  • 项目类别:
    Training Grant
BRC-BIO: Establishing Astrangia poculata as a study system to understand how multi-partner symbiotic interactions affect pathogen response in cnidarians
BRC-BIO:建立 Astrangia poculata 作为研究系统,以了解多伙伴共生相互作用如何影响刺胞动物的病原体反应
  • 批准号:
    2312555
  • 财政年份:
    2024
  • 资助金额:
    $ 75.52万
  • 项目类别:
    Standard Grant
RII Track-4:NSF: From the Ground Up to the Air Above Coastal Dunes: How Groundwater and Evaporation Affect the Mechanism of Wind Erosion
RII Track-4:NSF:从地面到沿海沙丘上方的空气:地下水和蒸发如何影响风蚀机制
  • 批准号:
    2327346
  • 财政年份:
    2024
  • 资助金额:
    $ 75.52万
  • 项目类别:
    Standard Grant
Graduating in Austerity: Do Welfare Cuts Affect the Career Path of University Students?
紧缩毕业:福利削减会影响大学生的职业道路吗?
  • 批准号:
    ES/Z502595/1
  • 财政年份:
    2024
  • 资助金额:
    $ 75.52万
  • 项目类别:
    Fellowship
感性個人差指標 Affect-X の構築とビスポークAIサービスの基盤確立
建立个人敏感度指数 Affect-X 并为定制人工智能服务奠定基础
  • 批准号:
    23K24936
  • 财政年份:
    2024
  • 资助金额:
    $ 75.52万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Insecure lives and the policy disconnect: How multiple insecurities affect Levelling Up and what joined-up policy can do to help
不安全的生活和政策脱节:多种不安全因素如何影响升级以及联合政策可以提供哪些帮助
  • 批准号:
    ES/Z000149/1
  • 财政年份:
    2024
  • 资助金额:
    $ 75.52万
  • 项目类别:
    Research Grant
How does metal binding affect the function of proteins targeted by a devastating pathogen of cereal crops?
金属结合如何影响谷类作物毁灭性病原体靶向的蛋白质的功能?
  • 批准号:
    2901648
  • 财政年份:
    2024
  • 资助金额:
    $ 75.52万
  • 项目类别:
    Studentship
Investigating how double-negative T cells affect anti-leukemic and GvHD-inducing activities of conventional T cells
研究双阴性 T 细胞如何影响传统 T 细胞的抗白血病和 GvHD 诱导活性
  • 批准号:
    488039
  • 财政年份:
    2023
  • 资助金额:
    $ 75.52万
  • 项目类别:
    Operating Grants
New Tendencies of French Film Theory: Representation, Body, Affect
法国电影理论新动向:再现、身体、情感
  • 批准号:
    23K00129
  • 财政年份:
    2023
  • 资助金额:
    $ 75.52万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
The Protruding Void: Mystical Affect in Samuel Beckett's Prose
突出的虚空:塞缪尔·贝克特散文中的神秘影响
  • 批准号:
    2883985
  • 财政年份:
    2023
  • 资助金额:
    $ 75.52万
  • 项目类别:
    Studentship
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了