Early and life course socioeconomic adversity and dementia risk in Hispanic/Latinos
西班牙裔/拉丁裔的早期和生命历程社会经济逆境和痴呆风险
基本信息
- 批准号:10831329
- 负责人:
- 金额:$ 41.95万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-08-15 至 2025-07-31
- 项目状态:未结题
- 来源:
- 关键词:AccelerationAddressAdministrative SupplementAdultAlzheimer&aposs disease related dementiaAlzheimer&aposs disease riskAreaBehaviorCOVID-19 vaccineCognitive agingCommunicationCommunitiesDiscriminationDistantEnglandEnrollmentEthicsEugenicsFailureGeneticGenetic studyGenomicsGoalsHeightHispanicHumanImpaired cognitionIndividualLatinoLatino PopulationLegalLifeLife Cycle StagesLinkMarmotaMeasuresMethodsMinority GroupsMinority Health ResearchModelingObservational StudyObservational epidemiologyOutcomeParentsPoliciesPopulation HeterogeneityPovertyPublic Health PracticeResearchResearch PersonnelRiskSeminalSocial EnvironmentSocial ResponsibilitySocietiesStigmatizationVoiceWorkburden of illnesscommunity engagementdementia riskdesigndissemination strategyearly detection biomarkersepidemiology studyexperiencehealth assessmenthealth disparityhealth equityhealth inequalitiesimprovedinnovationmembermultidisciplinaryparent grantsocial disparitiessocial epidemiologysocial health determinantssocial influencesocial stigmasocioeconomic adversitysocioeconomicstooltraitvaccine hesitancy
项目摘要
ABSTRACT
The goals of this administrative supplement to Early and Life Course Adversities and Dementia Risk in Latinos
(1RF1AG077639; contact PI: Isasi) are to (1) address Ethical, Legal, and Societal Implications (ELSI) of
research examining social determinants of health and Alzheimer's Disease and Related Dementias (ADRD)
risk, and (2) develop methods to assess health equity impact of the research. Social epidemiology has been at
the forefront of the identification of health disparities and research to understand its root causes. However, this
area of social epidemiology brings the risks of unintended individual, bystander and groups harms by
contributing to perpetuating the stigma associated with poverty and experienced by minoritized populations,
such as the Hispanic/Latino population. These unintended risks can emerge when: (1) findings regarding
disproportionate ADRD risk are interpreted as failures of the individual rather than of society, (2) findings are
misused or misinterpreted to exacerbate stigmatizing and discriminatory practices, (3) we fail to integrate
community voices and recognize the social context, such as the experience of living with poverty. This
administrative supplement aims to address this important research gap by implementing a model for the co-
design of the study's dissemination strategies and for the interpretation of study results. In addition, this
supplement brings a multidisciplinary perspective building on the ELSI framework. Furthermore, it also
addresses the potential risk of stigma and discrimination based on identified cognitive decline, which may limit
participation cognitive aging and ADRD research for minoritized populations. Another challenge of
observational epidemiological research is that it may be perceived as distant from public health practice,
without a direct action for improving health equity in ADRD or other outcomes. Furthermore, methods for
assessing the health equity impact of observational studies are still lacking. This supplement will adapt a model
for assessing the potential health equity impact of the parent study. In this supplement, we leverage our team
ELSI expertise and the Bridging Research, Accurate Information and Dialogue (BRAID) approach, an
innovative model for incorporating community member perspectives. BRAID will be used to bring community
voices to address the potential for individual and group harms, including stigma, and to move from a deficits
model to a community assets model that aligns epidemiological research with community needs, as we
effectively communicate study findings to maximize impact on structural or policy changes.
摘要
这一行政补充的目标,以早期和生命过程中的粘着和痴呆症的风险在拉丁美洲人
(1 RF 1AG 077639;联系PI:Isasi)旨在(1)解决以下问题的伦理、法律的和社会影响(ELSI)
研究检查健康和阿尔茨海默病及相关痴呆症(ADRD)的社会决定因素
风险,(2)制定方法来评估研究的健康公平影响。社会流行病学一直在
确定健康差距和研究以了解其根源的最前沿。但这
社会流行病学领域带来了意外的个人,旁观者和群体伤害的风险,
助长了与贫穷有关的和少数群体所经历的耻辱的长期存在,
例如西班牙裔/拉丁裔人口。这些意外的风险可能会出现,当:(1)调查结果
不成比例的ADRD风险被解释为个人而不是社会的失败,(2)调查结果是
滥用或误解,加剧污名化和歧视性做法,(3)我们未能融入
社区的声音,并承认社会背景,如生活在贫困中的经验。这
行政补充旨在通过实施一个共同的模式来解决这一重要的研究差距,
设计研究的传播战略和解释研究结果。另外这款
该补编在ELSI框架的基础上提出了多学科的观点。此外,它还
解决了基于已确定的认知能力下降的羞辱和歧视的潜在风险,这可能会限制
参与认知老化和少数群体的ADRD研究。的另一个挑战
观察性流行病学研究可能被视为远离公共卫生实践,
没有采取直接行动改善ADRD或其他结果的卫生公平性。此外,
仍然缺乏对观察性研究的健康公平影响的评估。本补充将采用一种模式
用于评估母研究的潜在健康公平性影响。在本补充中,我们利用我们的团队
ELSI的专业知识和桥接研究,准确的信息和对话(BRAID)方法,
结合社区成员观点的创新模式。BRAID将被用于将社区
声音,以解决个人和群体的伤害,包括耻辱,并从赤字,
模型到社区资产模型,使流行病学研究与社区需求保持一致,因为我们
有效地传播研究结果,以最大限度地影响结构或政策变化。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Charles DeCarli其他文献
Charles DeCarli的其他文献
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{{ truncateString('Charles DeCarli', 18)}}的其他基金
Do Atmospheric Ultrafine Particles Lodge in the Brain and Cause Cognitive Decline Leading to Alzheimer's Disease Related Dementias?
大气超细颗粒是否会滞留在大脑中并导致认知能力下降,从而导致阿尔茨海默病相关的痴呆症?
- 批准号:
10591354 - 财政年份:2022
- 资助金额:
$ 41.95万 - 项目类别:
Study of Latinos-Investigation of Neurocognitive Aging-Alzheimer's disease
拉丁裔研究-神经认知衰老-阿尔茨海默病的调查
- 批准号:
10629449 - 财政年份:2022
- 资助金额:
$ 41.95万 - 项目类别:
Study of Latinos-Investigation of Neurocognitive Aging-Alzheimer's disease
拉丁裔研究-神经认知衰老-阿尔茨海默病的调查
- 批准号:
10370841 - 财政年份:2022
- 资助金额:
$ 41.95万 - 项目类别:
Early and life course socioeconomic adversity and dementia risk in Hispanics/Latinos
西班牙裔/拉丁裔的早期和生命历程社会经济逆境和痴呆风险
- 批准号:
10445900 - 财政年份:2022
- 资助金额:
$ 41.95万 - 项目类别:
UC Davis Alzheimer's Disease Research Center
加州大学戴维斯分校阿尔茨海默病研究中心
- 批准号:
10461120 - 财政年份:2021
- 资助金额:
$ 41.95万 - 项目类别:
UC Davis Alzheimer's Disease Research Center
加州大学戴维斯分校阿尔茨海默病研究中心
- 批准号:
10666428 - 财政年份:2021
- 资助金额:
$ 41.95万 - 项目类别:
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