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中文摘要
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项目总结/摘要 本申请是为了响应特别利益通知(NOSI)而提交的,该通知被确定为 NOT-CA-23-044。 斯坦福大学癌症研究所(SCI)[2 P30 CA 124435 -14]的使命是利用广泛而独特的 斯坦福大学在基础科学、生物工程、人口科学、生物统计学、技术 开发,临床研究,临床护理和翻译,以(1)提高诊断,治疗, 癌症患者的结果;(2)了解不同人群中的癌症病因;(3)减少 SCI集水区及以外地区的癌症发病率。SCI致力于了解和解决 癌症负担和减少我们社区的癌症差异。这一提议是对一项 SCI社区咨询委员会要求促进关于减少 在病人和社区一级的集水区获得循证癌症护理服务。 过去30年的癌症研究发现刺激了癌症预防的关键创新 和医疗服务,大大提高了癌症患者的存活率。然而,癌症负担最重的社区 往往是最后一个从这些创新中受益的人。社区福利政策,包括医疗财政政策 援助和社区建设倡议,旨在激励医院系统解决以下需求: 服务不足的患者和社区。然而,这些政策在解决持久性 在癌症护理的获得和负担方面的差异在很大程度上是未知的。 基于我们先前对社区福利的研究,该提案旨在让社区和健康参与其中, 系统合作伙伴制定更加注重公平的社区福利政策,以改善癌症 成果,缩小差距。具体来说,我们试图了解复杂和相互作用的因素, 推动社区福利支出,以便为10个县的SCI中以公平为重点的分配决策提供信息 集水区本研究补编中提出的活动将为今后的研究奠定基础 研究开发和验证一个基于模拟的工具,为社区利益的分配提供信息, 更好地解决癌症患者的关键财政援助需求,并促进更公平的分配, 社区福利资源。
英文摘要
Project Summary/Abstract This application is being submitted in response to the Notice of Special Interest (NOSI) identified as NOT-CA-23-044. The Stanford Cancer Institute’s (SCI) [2P30CA124435-14] mission is to leverage the broad and unique strengths of Stanford University in basic science, bioengineering, population science, biostatistics, technology development, clinical research, clinical care, and translation to (1) improve the diagnosis, treatment, and outcomes of cancer patients; (2) understand cancer etiologies among diverse populations; and (3) decrease cancer incidence in the SCI catchment area and beyond. SCI is committed to understanding and addressing the cancer burden and reducing cancer disparities in our community. This proposal is in direct response to a request from the SCI Community Advisory Board to foster research on strategies to reduce disparities in access to evidence-based cancer care services in the catchment area at the patient and community level. Cancer research discoveries over the last 30 years have stimulation critical innovations in cancer prevention and care delivery, greatly improving cancer survival. However, communities with the greatest cancer burden are often last to benefit from these innovations. Community benefit policies, including medical financial assistance and community-building initiatives, aim to incentivize hospital systems to address the needs of underserved patients and communities. Yet, the effectiveness of these policies in addressing persistent disparities in cancer care access and burden are largely unknown. Building on our prior research on community benefits, this proposal aims to engage community and health system partners in the development of more equity-focused community benefit policies to improve cancer outcomes and reduce disparities. Specifically, we seek to understand the complex and interacting factors that drive community benefit spending in order to inform equity-focused allocation decisions in the 10-county SCI catchment area. Activities proposed in this research supplement will establish a foundation for future research studies to develop and validate a simulation-based tool to inform the allocation of community benefits in ways that better address critical financial assistance needs for cancer patients and foster a more equitable allocation of community benefit resources.
期刊论文(553)
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科研奖励(0)
会议论文
DOI: 10.1038/s41598-022-11800-w
发表时间: 2022-05-16
期刊: Scientific reports
影响因子: 4.6
作者: []
通讯作者:
DOI: 10.1016/j.canlet.2013.12.020
发表时间: 2014-04-28
期刊: CANCER LETTERS
影响因子: 9.7
作者: [Hu, Xiang, Liu, Yang, Qin, Chunxia, Pan, Zhenyu, Luo, Jun, Yu, Aixi, Cheng, Zhen]
通讯作者: Cheng, Zhen
DOI: 10.1038/s41598-018-27946-5
发表时间: 2018-07-03
期刊: Scientific reports
影响因子: 4.6
作者: [Banerjee I, Gensheimer MF, Wood DJ, Henry S, Aggarwal S, Chang DT, Rubin DL]
通讯作者: Rubin DL
DOI: 10.1177/1740774512437252
发表时间: 2012-04
期刊: Clinical trials (London, England)
影响因子: --
作者: [Lai TL, Lavori PW, Shih MC, Sikic BI]
通讯作者: Sikic BI
共 355 条
    Project 2: Immune signals promoting pancreas cancer stemness and progression
    • 批准号:
      10704088
    • 项目类别:
    • 资助金额:
      $41.46万
    • 财政年份:
      2021
    • 负责人:
      STEVEN E ARTANDI
    • 依托单位:
    Project 2: Immune signals promoting pancreas cancer stemness and progression
    • 批准号:
      10456770
    • 项目类别:
    • 资助金额:
      $41.46万
    • 财政年份:
      2021
    • 负责人:
      STEVEN E ARTANDI
    • 依托单位:
    Determining the role of TCAB1 in shaping telomerase function
    • 批准号:
      10228562
    • 项目类别:
    • 资助金额:
      $47.01万
    • 财政年份:
      2017
    • 负责人:
      STEVEN E ARTANDI
    • 依托单位:
    Determining the role of TCAB1 in shaping telomerase function
    • 批准号:
      9927965
    • 项目类别:
    • 资助金额:
      $46.33万
    • 财政年份:
      2017
    • 负责人:
      STEVEN E ARTANDI
    • 依托单位:
    海外基金