CCCWFU Research Base Grant

CCCWFU研究基地资助

• 批准号: 6783476
• 负责人: EDWARD G SHAW
• 金额: $ 110.03万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-09-07 至 2007-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6783476
• 关键词: alternative medicine; brain neoplasms; cancer prevention; cancer rehabilitation /care; chemoprevention; clinical research; clinical trials; cooperative study; experimental designs; human subject; human therapy evaluation; lung neoplasms; medical outreach /case finding; neoplasm /cancer education; neoplasm /cancer therapy; pancreas neoplasms; patient oriented research; psychological aspect of cancer; quality of life

DESCRIPTION (provided by applicant): The Comprehensive Cancer Center of Wake Forest University (CCCWFU) Community Clinical Oncology Program (CCOP) Research Base was funded in 9/99 (retroactive to 6/99) for three years. This application describes the administrative structure, including safety and monitoring procedures and clinical research activities of the Research Base for its five-year competitive renewal as a control/treatment CCOP Research Base. Participants in the Research Base include three CCOPs (Southeast Cancer Control Consortium, Winston-Salem, NC; Upstate Carolina CCOP, Spartanburg, SC; Greenville CCOP, Greenville SC) and four non-CCOP Prevention Members (East Carolina University, Greenville, NC; High Point Regional Health System, High Point, NC; InterCommunity Cancer Center, Rome, GA; WakeMed System, Cary, NC. The geographic region covered by these three CCOPs and four Prevention Members includes seven states (NC, SC, VA, WV, KY, TN, GA) with a population of approximately 12 million people, one-quarter of whom are minorities (60% minorities in coastal NC communities), served by 28 cancer centers. It is anticipated that an additional 3-6 CCOPs and Minority-Based CCOPs will join the CCCWFU CCOP Research Base by 12/01. Active and developing clinical trials of the Research Base are described in the application. In cancer control, there are 4 active and 13 developing studies, focusing on the following areas: complimentary and alternative medicine, symptom management, and quality of life, particularly in the setting of cancer related fatigue, anorexia/weight loss, depression, hot flashes, cognition and chemoprevention. In cancer treatment, there are 6 active and 7 developing studies, focusing on complementary, alternative, and conventional therapies primarily in lung, pancreas, and brain cancer. The spectrum of clinical research studies offered by the CCCWFU CCOP Research Base is complementary to, rather than competitive with, the cancer control/treatment protocols offered by the Cooperative Group Research Bases. Under the direction of Principal Investigator Edward G. Shaw, M.D., the Clinical Research Management administrative structure of the CCCWFU, and key leadership from the CCCWFU, CCOPs, and Prevention Members, the CCCWFU CCOP Research Base is fulfilling its primary goal of providing state-of-the-art intervention oriented clinical research studies in cancer prevention/control to CCOPs and patients (including minorities) in the Southeast United States.

描述（由申请人提供）： Wake Forest大学（CCCWFU）综合癌症中心社区临床肿瘤计划（CCOP）研究基础在9/99（追溯至6/99）为期三年。该应用程序描述了行政结构，包括其五年竞争性更新作为对照/治疗CCOP研究基础的研究基础的安全和监测程序以及研究基础的临床研究活动。 Participants in the Research Base include three CCOPs (Southeast Cancer Control Consortium, Winston-Salem, NC; Upstate Carolina CCOP, Spartanburg, SC; Greenville CCOP, Greenville SC) and four non-CCOP Prevention Members (East Carolina University, Greenville, NC; High Point Regional Health System, High Point, NC; InterCommunity Cancer Center, Rome, GA; WakeMed System, Cary, NC.这三个CCOP和四名预防成员涵盖的地理区域包括七个州（NC，SC，， VA，WV，KY，TN，GA），人口约1200万人，其中四分之一是少数民族（沿海NC社区中的60％少数民族），由28个癌症中心服务。预计，额外的3-6个CCOP和少数族裔的CCOP将会以12/01加入CCCWFU CCOP研究基础。应用程序中描述了研究基础的积极和发展的临床试验。在癌症控制中，有4个活跃和13个发展 研究，专注于以下领域：免费和替代医学，症状管理和生活质量，尤其是在癌症相关疲劳，厌食/体重减轻，抑郁，炎热，认知和化学预防的情况下。在癌症治疗中，有6项活跃和7项正在进行的研究，重点是互补，替代和常规疗法，主要是在肺，胰腺和脑癌中。频谱 CCCWFU CCOP研究基础提供的临床研究基础是合作小组研究基础提供的癌症控制/治疗方案而不是竞争的临床研究。在首席研究员爱德华·肖（Edward G. CCCWFU和预防成员来自CCCWFU CCOP研究基础 在美国东南部为CCOPS和患者（包括少数群体）提供面向癌症预防/控制的最新干预临床研究的主要目标。