Michigan Center for Integrative Approaches to Health Disparities (CIAHD)

描述（由申请人提供）：不同种族/民族的健康状况存在持续和明显的差异（通常称为健康差异），导致多种健康结果。尽管对这些差异的记录反复出现，但对其背后的驱动力仍存在大量争论。确定产生这些差异的因素对改善少数民族人口健康和减少差异的干预措施和政策具有明显的影响。人们越来越意识到，不仅从科学理解的角度来看，而且从确定减少现实世界中差异的最有效战略的角度来看，目前理解这些差异的方法是不够的，这些方法往往试图将问题分解为不同的社会和生物组成部分。了解健康差异需要综合考虑社会和生物因素；不仅要考虑个人特征，还要考虑个人生活和工作的多种环境的特征。密歇根健康差异综合方法中心（CIAHD）的首要目标是促进和支持在多层次框架内全面整合社会和生物因素的研究，以了解少数民族健康和健康差异的决定因素。虽然该中心最初将专注于将该模型应用于心血管风险，但它为所有少数民族健康和健康差异研究人员提供了一个有用的框架。这种多层次综合方法对于确定最有可能改善少数群体健康和减少健康差距的干预措施和战略至关重要。这一总体目标将通过一系列相互关联的目标来实现。目的1。促进对社会和生物因素的相互关系如何影响少数民族人群的健康和健康差异的科学理解，特别关注心血管风险。目标2。在密歇根大学和杰克逊心脏研究中心（通过其合作伙伴杰克逊州立大学和密西西比大学医学中心）之间建立互利的合作伙伴关系，在我们的多层次综合框架内推进研究和培训。目标3。创建一个论坛，在整合社会和生物因素的多层次框架的总体框架下，广泛整合和集中密歇根大学和我们的合作机构正在进行的少数民族健康和健康差异研究。目标4。向生物医学和健康研究界以及一般公众传播多层次综合范式。这些目标将通过行政核心和研究核心来实现。行政核心将提供领导和协调，并将组织培训以及机构内和机构间交流。研究核心将包括与总体主题相关的三个研究项目（其中一个是密歇根大学和JHS之间的合作项目）、试点项目和统计支持。

DESCRIPTION (provided by applicant): Persistent and pronounced differences in health by race/ethnicity (often termed health disparities) exist for multiple health outcomes. Despite repeated documentation of these disparities, there is still substantial debate on the driving forces behind them. Identifying the factors that generate these disparities has obvious implications for interventions and policies to improve health in minority populations and reduce disparities. There is a growing sense that current approaches to understanding these disparities, which often attempt to fragment the problem into distinct social and biological components, are insufficient, not only from the point of view of scientific understanding, but also from the point of view of identifying the most effective strategies to reduce disparities in the real world. Understanding health disparities will require integration of social and biological factors; as well as consideration, not only of individual characteristics, but also characteristics of the multiple contexts in which individuals live and work. The overarching goal of the Michigan Center for Integrative Approaches to Health Disparities (CIAHD) is to promote and support research that comprehensively integrates social and biological factors within a multilevel framework in understanding the determinants of minority health and health disparities. Although the center will initially focus on applying this model to cardiovascular risk, it provides a framework useful to all minority health and health disparities researchers. This multilevel integrated approach is crucial to identifying the interventions and strategies most likely to improve minority health and reduce health disparities. This overarching goal will be achieved through a set of interrelated Aims. Aim 1. To advance scientific understanding of how the interrelation of social and biologic factors contributes to health in minority populations and health disparities with a specific focus on cardiovascular risk. Aim 2. To establish a mutually beneficial partnership between the University of Michigan and the Jackson Heart Study (JHS) (through its partners Jackson State University and the University of Mississippi Medical Center) to advance research and training within our multilevel integrated framework. Aim 3. To create a forum that will integrate and centralize ongoing minority health and health disparities research broadly at the University of Michigan and our partner institutions under the general umbrella of a multilevel framework that integrates social and biological factors. Aim 4. To disseminate the multilevel integrated paradigm to the biomedical and health research community, as well as to the public generally. These aims will be achieved through an Administrative Core and a Research Core. The Administrative Core will provide leadership and coordination and will organize training, as well as intra-and-inter-institutional exchanges. The Research Core will include three research projects linked to the overall theme (one of which is a partnership between the University of Michigan and JHS), pilot projects, and statistical support.