INTRACELLULAR RNA TRAFFICKING

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 RNA运输是一个复杂的过程，通过这个过程，特定的RNA被定位到特定的亚细胞室。通过各种体内和体外技术，我们描绘了描述神经细胞中RNA运输系统的分子相互作用图。该项目旨在根据实验确定的每一种相互作用的参数，开发有意义的RNA运输计算模型。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. RNA trafficking is a complex process whereby specific RNAs are localized to particular subcellular compartments. Through a variety of in vivo and in vitro techniques we have delineated a molecular interaction map describing the RNA trafficking system in neural cells. This project is to develop meaningful computational models for RNA trafficking based on experimentally determined parameters for each of the interactions.