Biomedical Informatics

生物医学信息学

• 批准号: 7714118
• 负责人: THEODORE G KRONTIRIS
• 金额: $ 10.71万
• 依托单位: BECKMAN RESEARCH INSTITUTE/CITY OF HOPE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-01 至 2012-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7714118
• 关键词: Adverse event; Architecture; Area; Basic Science; Bioinformatics; Biotechnology; Budgets; Cancer Center; Cancer Center Support Grant; Cities; Classification; Clinical; Clinical Research; Clinical Trials; Collaborations; Collection; Computer Hardware; Computer software; Computers; Databases; Depth; Development; Equipment; Evaluation; Fees; Funding; Funding Opportunities; Human Resources; Imagery; Individual; Informatics; Information Management; International; Internet; Intranet; Joints; Modeling; Peer Review; Performance; Policies; Process; Publications; Range; Reporting; Research; Research Personnel; Resource Sharing; Resources; Retrieval; Secure; Shared Resource Cancer Center; Specialist; Standards of Weights and Measures; Supercomputing; System; Systems Analysis; Systems Biology; Technology; Training Programs; Translational Research; Vendor; Work; base; biomedical informatics; cancer Biomedical Informatics Grid; cost effectiveness; data integration; data management; improved; informatics training; member; open source; platform-independent; programs; size

The Biomedical Informatics Core was established in 1998 to meet the information management needs of Cancer Center investigators. The Core provides a broad range of hardware, software and personnel resources that serve many investigators and several other shared resource facilities. The Core also works in collaboration with City of Hope and Cancer Center governance committees to promulgate standards, optimize systems and minimize redundancy through continued integration of data, databases, applications and processes. Over the last five years, BIC has become the most widely used Cancer Center shared resource, and Core usage continues to increase each year. A new subscription-based chargeback policy was implemented in October 2003, and chargeback revenue has increased from $7,250 in 2003 to $66,700 in 2006. Since the last competitive renewal, over 1/4 (276/1001) of all Cancer Center peer-reviewed publications involved the use of informatics shared resources. Throughout this evaluation period, the Core has significantly expanded the depth, breadth and cost-effectiveness of support for Center research. Examples include (1) new Citrix-based software deployment technologies that replace hundreds of software installations on individual workstations and provide secure, platform-independent, remote access to Core resourcess via the Internet and City of Hope intranet; (2) a new research and technology collaboration with the San Diego Supercomputing Center to pursue joint funding opportunities and host the Core's most computationally-intensive bioinformatics applications on the TeraGrid national supercomputing network; (3) development and delivery of more than 20 end-user training programs in collaboration with commercial software vendors and the National Center for Biotechnology Information (NCBI); and (4) funded participation in the caBIG Clinical Trials Management Systems (CTMS) workspace to develop workflows, information models and open-source software applications to facilitate Adverse Event (AE) reporting on a national scale. During FY 2006, the Core provided informatics support for 135 Cancer Center members; 76% of the users supported by biomedical informatics had peer-reviewed funding. Annual budget for the core is $2,065,231 (44% institutional, 3% user fees, 45% other), with 7% ($151,000) requested from the CCSG.

生物医学信息学核心成立于1998年，以满足信息管理的需要， 癌症中心的研究人员。核心提供广泛的硬件、软件和人员 为许多调查人员和其他几个共享资源设施服务的资源。核心还在 与希望之城和癌症中心管理委员会合作，颁布标准， 通过持续集成数据、数据库和应用程序， 和过程。在过去的五年里，BIC已成为最广泛使用的癌症中心共享 核心资源的使用量每年都在不断增加。新的基于订阅的退款政策 2003年10月实施，收费收入从2003年的7，250美元增加到66，700美元 图：2006年自上次竞争性更新以来，超过1/4（276/1001）的癌症中心同行评审 出版物涉及使用信息学共享资源。在整个评估期间， 大大扩展了对中心研究的支持的深度、广度和成本效益。 例子包括：（1）基于Citrix的新软件部署技术， 安装在各个工作站上，并提供安全、独立于平台的远程访问Core 透过互联网及City of Hope内联网获取资源;（2）与 圣地亚哥超级计算中心寻求联合资助机会，并举办核心的最 TeraGrid国家超级计算网络上的计算密集型生物信息学应用;（3） 开发和交付20多个最终用户培训计划，与商业合作， 软件供应商和国家生物技术信息中心（NCBI）;（4）资助参与 在caBIG临床试验管理系统（CTMS）工作区中， 模型和开源软件应用程序，以促进全国范围内的不良事件（AE）报告。 在2006财政年度，核心为135个癌症中心成员提供了信息支持; 76%的用户 由生物医学信息学支持的一个项目得到了同行评审的资助。核心资源的年度预算为2 065 231美元 (44机构费用占3%，用户费用占3%，其他费用占45%），其中7%（151，000美元）由CCSG提供。