Biomedical Informatics

生物医学信息学核心成立于1998年，旨在满足 癌症中心的调查人员。核心提供广泛的硬件、软件和人员 为许多调查人员和其他几个共享资源设施提供服务的资源。核心还可以在 与希望之城和癌症中心治理委员会合作发布标准， 通过持续集成数据、数据库、应用程序来优化系统并最大限度地减少冗余 和流程。在过去的五年里，BIC已经成为使用最广泛的癌症共享中心 资源，核心使用量每年都在持续增加。新的基于订阅的按存储容量使用计费策略 于2003年10月实施，按存储容量使用计费收入从2003年的7,250美元增加到66,700美元 在2006年。自上次竞争更新以来，超过四分之一(276/1001)的所有癌症中心接受了同行审查 出版物涉及使用信息学共享资源。在整个评估期内，核心 显著扩大了对中心研究的支持的深度、广度和成本效益。 例如(1)基于Citrix的新软件部署技术取代了数百个软件 安装在单个工作站上，并提供对Core的安全、独立于平台的远程访问 通过互联网和希望之城内联网获取资源；(2)与 圣地亚哥超级计算中心将寻求联合资助机会，并主办核心最 TeraGrid国家超级计算网络上的计算密集型生物信息学应用；(3) 与商业银行合作，开发和提供20多个最终用户培训计划 软件供应商和国家生物技术信息中心(NCBI)；以及(4)资助参与 在caBIG临床试验管理系统(CTMS)工作空间中开发工作流、信息 促进在全国范围内报告不良事件(AE)的模型和开源软件应用程序。 在2006财年，该中心为135名癌症中心成员提供了信息学支持；76%的用户 在生物医学信息学的支持下，获得了同行评审的资金。核心的年度预算为2 065 231美元 (44%的机构费用，3%的用户费用，45%的其他费用)，7%(151,000美元)由CCSG申请。

The Biomedical Informatics Core was established in 1998 to meet the information management needs of Cancer Center investigators. The Core provides a broad range of hardware, software and personnel resources that serve many investigators and several other shared resource facilities. The Core also works in collaboration with City of Hope and Cancer Center governance committees to promulgate standards, optimize systems and minimize redundancy through continued integration of data, databases, applications and processes. Over the last five years, BIC has become the most widely used Cancer Center shared resource, and Core usage continues to increase each year. A new subscription-based chargeback policy was implemented in October 2003, and chargeback revenue has increased from $7,250 in 2003 to $66,700 in 2006. Since the last competitive renewal, over 1/4 (276/1001) of all Cancer Center peer-reviewed publications involved the use of informatics shared resources. Throughout this evaluation period, the Core has significantly expanded the depth, breadth and cost-effectiveness of support for Center research. Examples include (1) new Citrix-based software deployment technologies that replace hundreds of software installations on individual workstations and provide secure, platform-independent, remote access to Core resourcess via the Internet and City of Hope intranet; (2) a new research and technology collaboration with the San Diego Supercomputing Center to pursue joint funding opportunities and host the Core's most computationally-intensive bioinformatics applications on the TeraGrid national supercomputing network; (3) development and delivery of more than 20 end-user training programs in collaboration with commercial software vendors and the National Center for Biotechnology Information (NCBI); and (4) funded participation in the caBIG Clinical Trials Management Systems (CTMS) workspace to develop workflows, information models and open-source software applications to facilitate Adverse Event (AE) reporting on a national scale. During FY 2006, the Core provided informatics support for 135 Cancer Center members; 76% of the users supported by biomedical informatics had peer-reviewed funding. Annual budget for the core is $2,065,231 (44% institutional, 3% user fees, 45% other), with 7% ($151,000) requested from the CCSG.