DEVELOPMENT BEHAVIORAL & NEUROPHYSIOLOGICAL MEASURES FOR EARLY AUTISM DIAGNOSIS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 该项目比较了自闭症患者与使用眼球跟踪和事件相关电位技术的典型发育儿童的行为和神经过程，这些过程对于社会交流至关重要。我们将这一表现与猴子的表现进行了比较，猴子在年轻时和成年后都接受了选择性脑损伤。我们的目标是进一步了解参与社会交流的神经机制，以及这些机制如何在发育障碍中受到损害。 在过去的一年里，我们已经完成了所有人类参与者和猴子的行为和电生理数据的收集。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project compares behavioral and neural processes critical for social communication in autistic compared to typically developing children using eye tracking and ERP techniques. We have compared this performance to that of monkeys who have received selective brain lesions both as young individuals and as adults. Our goal is to further understand the neural mechanisms involved in social communication and how these may become impaired in developmental disorders. During this last year we have completed the collection of behavioral and electrophysiological data on all human participants and on the monkeys.