SUBCLINICAL ATHEROSCLEROSIS IN HIV INFECTED MEN

HIV 感染男性的亚临床动脉粥样硬化

• 批准号: 7731277
• 负责人: STEVEN K. GRINSPOON
• 金额: $ 10.06万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7731277
• 关键词: Atherosclerosis; Cardiovascular Diseases; Cohort Studies; Computer Retrieval of Information on Scientific Projects Database; Coronary Arteriosclerosis; Funding; Genetic; Grant; HIV; Inflammatory; Institution; Metabolic; Patients; Prevalence; Research; Research Design; Research Personnel; Resources; Source; United States National Institutes of Health; men

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We propose to investigate the prevalence of subclinical coronary atherosclerosis in young HIV-infected patients without previously known cardiovascular disease. We also propose to study the potential metabolic, inflammatory, and genetic factors that may be associated with atherosclerosis in HIV-infected patients. The study design is an observational cross-sectional cohort study to examine the prevalence of early atherosclerotic coronary artery disease using MSCT in 100 HIV infected men as compared to 50 normal healthy control men.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 我们建议调查年轻的HIV感染者中无已知心血管疾病的亚临床冠状动脉粥样硬化的患病率。 我们还建议研究可能与HIV感染患者动脉粥样硬化相关的潜在代谢、炎症和遗传因素。 研究设计是一项观察性横断面队列研究，旨在使用MSCT检查100名HIV感染男性与50名正常健康对照男性中早期动脉粥样硬化性冠状动脉疾病的患病率。