SUBCLINICAL ATHEROSCLEROSIS IN HIV INFECTED MEN

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 我们建议调查无心血管疾病的年轻HIV感染患者中亚临床冠状动脉粥样硬化的患病率。我们还建议研究潜在的代谢、炎症和遗传因素，这些因素可能与HIV感染患者的动脉粥样硬化有关。 这项研究设计是一项观察性横断面队列研究，旨在通过MSCT检查100名HIV感染男性和50名正常健康对照组男性早期动脉粥样硬化性冠状动脉疾病的患病率。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We propose to investigate the prevalence of subclinical coronary atherosclerosis in young HIV-infected patients without previously known cardiovascular disease. We also propose to study the potential metabolic, inflammatory, and genetic factors that may be associated with atherosclerosis in HIV-infected patients. The study design is an observational cross-sectional cohort study to examine the prevalence of early atherosclerotic coronary artery disease using MSCT in 100 HIV infected men as compared to 50 normal healthy control men.