Integration, Planning and Oversight of Core Activities

行政核心 摘要： 这项UTSW视觉研究核心补助金的总体目标是提高视觉的能力， 研究科学家，方便他们获得设备、培训和技术支持，这将： 实验能力，推进科学严谨性，导致更具成本效益和时间效率的研究， 开辟新的研究方向。核心补助金亦有助维持一个肥沃的环境， 培养年轻的视觉研究人员，并促进UTSW视觉科学家之间的新合作 和其他机构在达拉斯/英尺。值得大都市。 我们提议的NEI核心中心由三个资源/服务模块组成，每个模块均由一名教师指导 在其单位重点领域具有经验和专业知识的成员：1）细胞培养和细胞表型分析; 2） 分子生物学/病毒生产;以及，3）显微镜和数字成像。此外，该中心还包括一个 生物统计学家，将与每名研究者一起设计其研究，以及 并计划对他们的数据进行严格的分析和对结果的解释。W.马修·佩特罗 哲学博士、行政核心和中心主任的主要研究者将负责 核心中心和NEI P30补助金的管理。Petroll博士将监督部门秘书 以及为中心活动提供行政支持的行政人员。这将包括：1） 安排设备维护、管理服务合同和采购供应品，以支持这三个方面 科学模块; 2）安排与核心资助活动有关的会议; 3）维持预算， 每月向Petroll博士和三位模块主任提供支出摘要。彼得罗医生会等着 每月召开模块主管会议，解决可能出现的任何问题，以确保 优先事项得到满足，模块得到大量使用，并确定引入新项目的机会 到中心。他亦会主持核心拨款咨询委员会每半年举行一次的会议， 就技术问题提供意见，并对可能出现的任何严重冲突作出裁决。此外，本发明还提供了一种方法， 咨询委员会成员与各学科的研究人员有着密切的联系， 独特的定位，以确定和促进潜在的多学科合作，并建议 采用新技术和工艺。 核心补助金的成功与否将通过以下结果衡量标准进行评估： 利用每个模块; B）受益于一个或多个模块的出版物数量; c） 由核心补助金支持的试点研究，最终获得新的NEI研究赠款金，或 私人基金会赠款; d）博士后研究员、医科学生和研究生的人数， 有效地利用了每个模块;以及e）论文研究依赖于支持的学生人数 一个或多个模块;以及完成博士学位的学生人数。在一个以NEI为中心的地区。

Administrative Core Abstract: The overall goal of this UTSW Core Grant for vision research is to enhance the capabilities of vision research scientists by facilitating easy access to equipment, training and technical support which will: expand experimental capabilities, advance scientific rigor, result in more cost-effective and time-efficient research, and open up new research directions. The Core Grant will also help to sustain a fertile environment for the development of young vision researchers and stimulate new collaborations between vision scientists at UTSW and other institutions in the Dallas/Ft. Worth metroplex. Our proposed NEI Core Center consists of three Resource/Service Modules, each directed by a faculty member with experience and expertise in their unit’s focus area: 1) Cell Culture and Cell Phenotyping; 2) Molecular Biology/Virus Production; and, 3) Microscopy and Digital Imaging. In addition, the Center includes a biostatistician who will work with each of the Investigators regarding the design of their research studies, and with planning for the rigorous analysis of their data and interpretation of their results. W. Matthew Petroll, Ph.D., Principal Investigator of the Administrative Core and Center Director, will be responsible for overall administration of the Core Center and of the NEI P30 grant. Dr. Petroll will oversee Departmental secretarial and administrative staff who will provide administrative support for Center activities. This will include: 1) arranging equipment maintenance, managing service contracts, and purchasing supplies to support all three scientific Modules; 2) scheduling meetings related to the Core Grant activities; 3) maintaining budgets and providing monthly summaries of expenditures to Dr. Petroll and the three Module Directors. Dr. Petroll will hold monthly meetings of the Module Directors to troubleshoot any problems that might arise, to ensure that priorities are satisfied and that Modules are heavily used, and to identify opportunities for bringing new projects to the Center. He will also host the semi-annual meetings of the Core Grant Advisory Committee, which will offer advice on technical issues and will serve to adjudicate any serious conflicts that might arise. In addition, the Advisory Committee members have strong connections to researchers in a variety of disciplines, and are uniquely positioned to identify and promote potential multi-disciplinary collaborations, and recommend the incorporation of new technologies and techniques. Success of the Core Grant will be assessed by the following outcome measures: a) number of participants utilizing each Module; b) number of publications that benefited from one or more of the Modules; c) number of pilot studies supported by the Core Grant that culminated in the awarding of new NEI research grants or private foundation grants; d) number of postdoctoral fellows, medical students, and graduate students that productively utilized each Module; and e) number of students whose dissertation research relied on the support of one or more Modules; and the number of these students who completed their Ph.D. in an NEI-focused area.