Genomics Facility Core

基因组学设施核心

• 批准号: 10392377
• 负责人: George S Watts
• 金额: $ 17.29万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-04-01 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10392377
• 关键词: Bioinformatics; Cells; Collaborations; Consultations; Core Facility; Custom; Data Analyses; Doctor of Philosophy; Environmental Health; Epigenetic Process; Experimental Designs; Gene Expression Profiling; Genes; Genetic Research; Genomics; Goals; Methodology; Methods; Mutation Detection; Nucleic Acids; Preparation; Protocols documentation; Quality Control; Research; Research Personnel; Sampling; Services; Techniques; Technology; Testing; Training and Education; Update; base; cost efficient; data management; deep sequencing; experience; functional genomics; genome analysis; innovation; member; microbiome analysis; new technology; next generation sequencing; novel; tool; whole genome

The Genomics Facility Core (GFC) provides the Southwest Environmental Health Sciences Center (SWEHSC) investigators with high quality, cutting-edge, custom genomic services and data analyses, and consultation on data analysis and training/education regarding genomic methods and bioinformatics. Overall, the objective of the GFC is to provide SWEHSC members with guided, cost-efficient access to a full spectrum of genomic technologies to facilitate novel and innovative research. To this end, the GFC was an early adopter of Next- Generation Sequencing (NGS) technologies and functional genomics studies, and offers a broad range of expertise to support the analysis of low-input and degraded materials as well as single-cell and other custom enrichment techniques. To enhance the functional genetics research conducted by SWEHSC members, the GFC provides numerous services such as deep sequencing, mutation detection, epigenetics, microbiome analysis, gene expression profiling, and copy number analysis. Likewise, the GFC provides support on all aspects of a study including sample isolation and quality control, all steps of the sample and data analysis, as well as on data management and confirmation of the results. Finally, in addition to assisting with established methodologies, the GFC develops and tests new technologies, platforms, and protocols in collaboration with the SWEHSC investigators.

基因组学院核心（GFC）提供了西南环境健康科学中心（SWEHSC） 具有高质量，尖端，自定义基因组服务和数据分析的调查员 有关基因组方法和生物信息学的数据分析和培训/教育。总体而言， GFC将为SWEHSC成员提供有指导性的，具有成本效益的访问权限 促进新颖和创新研究的技术。为此，全球金融危机是下一步的早期采用者 生成测序（NGS）技术和功能基因组学研究，并提供广泛的 专业知识，以支持低输入和退化材料以及单细胞和其他习俗的分析 丰富技术。为了增强SWEHSC成员进行的功能遗传学研究 GFC提供了许多服务，例如深度测序，突变检测，表观遗传学，微生物组 分析，基因表达分析和拷贝数分析。同样，GFC为所有人提供支持 研究的各个方面包括样本隔离和质量控制，样本的所有步骤和数据分析， 以及数据管理和结果确认。最后，除了协助建立 方法论，GFC与 SWEHSC调查人员。