Transdisciplinary Training in Sleep and Circadian Rhythms

摘要 这个新的科罗拉多大学跨学科培训计划的主要目的是准备优秀的 前（博士）和后（博士，医学博士/博士，医学博士）博士研究员的科学生涯，解决尖端的基础 以及代表生物医学研究未来的临床研究问题。培训计划将 促进跨学科研究与国家的最先进的技术和参与教师使用的方法 实验室，并将评估和提高早期职业教师的指导技能。该方案是新颖的， 它使来自不同生物医学研究背景的学员和教职员工接触到协作睡眠， 昼夜节律科学同样，目前的睡眠和昼夜节律的学员和专家教师受益于有意义的 与来自不同研究背景的研究人员的互动，特别是来自生物医学研究的研究人员 对NIH/NHLBI非常重要的领域。22个参与者的研究培训活动 教师强调睡眠和昼夜生理学的跨学科培训，重点研究项目 心血管、遗传学/基因组学、代谢组学、蛋白质组学、生物标志物开发、生物信息学， 生物统计学，流行病学，应激生理学，免疫学，内分泌学，代谢，肥胖症，糖尿病， 神经科学、儿科、发育、衰老、精神病学以及肺部和行为睡眠医学。 因为我们的目标是提供跨学科和转化研究的职业培训， 该T32的组成部分包括综合生理学系，心理学系和 神经科学，和行为遗传学研究所在科罗拉多大学博尔德，和多个临床 科罗拉多大学医学院安舒茨医学院的系和部门。的 现时富有成效的合作环境是这项培训补助金的优点。在现有的T32中， 科罗拉多大学，这将是唯一一个致力于跨学科的睡眠和昼夜节律科学。 此外，它将成为美国西部第一个睡眠和昼夜节律T32。 培训计划的具体目标是招募、选拔和留住优秀学员; 包容性卓越;提供高质量的培训，教育和职业发展经验，以准备 研究密集型和研究相关职业的受训人员;塑造明天的科学领导者;培养 严格和协作的睡眠和昼夜节律科学;确保学员成功地 在个人发展计划中定义的预定里程碑;提高教师的指导技能 通过正式的指导培训计划;确保认真的计划评估;并增加 研究人员进行跨学科的睡眠和昼夜节律科学。我们请求支持一个博士预科生 第一年有一名博士后培训生，第二至五年有两名博士预科生和两名博士后培训生。

ABSTRACT The primary aim of this new University of Colorado transdisciplinary training program is to prepare outstanding pre-(PhD) and post-(PhD, MD/PhD, MD) doctoral fellows for science careers that address cutting-edge basic and clinical research questions that represent the future of biomedical research. The training program will foster transdisciplinary research with state-of-the-art technologies and methods used by participating faculty laboratories, and will evaluate and enhance the mentoring skills of early career faculty. The program is novel in that it exposes trainees and faculty from diverse biomedical research backgrounds to collaborative sleep and circadian science. Similarly, current sleep and circadian trainees and expert faculty benefit from meaningful interactions with investigators from different research backgrounds, particularly those from biomedical research areas that are of high importance to the NIH/NHLBI. The research training activities of the 22 participating faculty emphasize transdisciplinary training in sleep and circadian physiology with research programs focused on cardiovascular, genetics/genomics, metabolomics, proteomics, biomarker development, bioinformatics, biostatistics, epidemiology, stress physiology, immunology, endocrinology, metabolism, obesity, diabetes, neuroscience, pediatrics, development, aging, psychiatry, and pulmonary and behavioral sleep medicine. Because our goal is to provide transdisciplinary and translational research career training, major program components of this T32 include the Department of Integrative Physiology, the Department of Psychology and Neuroscience, and the Institute for Behavioral Genetics at University of Colorado Boulder, and multiple clinical departments and divisions at University of Colorado School of Medicine Anschutz Medical Campus. The existing fruitful and collaborative environment is a strength of this training grant. Of the existing T32s at the University of Colorado, this would be the only one dedicated to transdisciplinary sleep and circadian science. Also, it would become the first sleep and circadian T32 in the Western United States. The specific aims of the training program are to recruit, select and retain outstanding trainees; promote inclusive excellence; provide high quality training, educational, and career development experiences to prepare trainees for research-intensive and research-related careers; shape tomorrow’s scientific leaders; foster rigorous and collaborative sleep and circadian science; ensure successful progress of trainees toward predetermined milestones defined in Individual Development Plans; enhance the mentoring skills of faculty through a formal mentoring training plan; ensure conscientious program evaluation; and expand the number of investigators conducting transdisciplinary sleep and circadian science. We request support for one pre-doctoral and one post-doctoral trainee in year 1, and two pre-doctoral and two post-doctoral trainees in years 2-5.