Transdisciplinary Training in Sleep and Circadian Rhythms

摘要 科罗拉多大学这一新的跨学科培训计划的主要目标是为优秀的 博士后(PHD)和博士后(PHD，MD/PhD，MD)，从事研究尖端基础知识的科学职业 以及代表生物医学研究未来的临床研究问题。培训计划将 利用最先进的技术和方法促进参与研究的教师进行跨学科研究 实验室，并将评估和加强早期职业教师的指导技能。该计划在以下方面很新颖 它使来自不同生物医学研究背景的受训者和教职员工接触到协作睡眠和 昼夜节律科学。同样，当前的睡眠和昼夜节律实习生和专家教员也受益于有意义的 与来自不同研究背景的研究人员，特别是生物医学研究人员的互动 对NIH/NHLBI具有高度重要性的领域。22名参赛者的科研培训活动 教职员工强调睡眠和昼夜生理学方面的跨学科培训，重点是研究项目 心血管、遗传学/基因组学、代谢组学、蛋白质组学、生物标记物开发、生物信息学、 生物统计学、流行病学、压力生理学、免疫学、内分泌学、新陈代谢、肥胖、糖尿病、 神经科学、儿科学、发育、衰老、精神病学以及肺部和行为睡眠医学。 因为我们的目标是提供跨学科和翻译研究职业培训，主要项目 T32的组成包括综合生理学系、心理学系和 和科罗拉多博尔德大学行为遗传学研究所，以及多个临床 科罗拉多大学医学院安舒茨医学院院系。这个 现有的富有成效和协作的环境是这笔培训赠款的优势。现有的T32在 这将是唯一一所致力于跨学科睡眠和昼夜节律科学的大学。 此外，它还将成为美国西部第一个睡眠和昼夜节律T32。 培训计划的具体目标是招募、选拔和留住优秀的学员；促进 包容性卓越；提供高质量的培训、教育和职业发展经验，为 为研究密集型和与研究相关的职业培训；塑造未来的科学领袖；培养 严谨和协作的睡眠和昼夜节律科学；确保学员成功地朝着 个人发展计划中预先确定的里程碑；提高教师的指导技能 通过正式的辅导培训计划；确保认真的计划评估；并扩大 研究人员进行跨学科的睡眠和昼夜节律科学研究。我们请求支持一名博士后 一年级一名博士后实习生，二至五年级两名博士后和两名博士后实习生。

ABSTRACT The primary aim of this new University of Colorado transdisciplinary training program is to prepare outstanding pre-(PhD) and post-(PhD, MD/PhD, MD) doctoral fellows for science careers that address cutting-edge basic and clinical research questions that represent the future of biomedical research. The training program will foster transdisciplinary research with state-of-the-art technologies and methods used by participating faculty laboratories, and will evaluate and enhance the mentoring skills of early career faculty. The program is novel in that it exposes trainees and faculty from diverse biomedical research backgrounds to collaborative sleep and circadian science. Similarly, current sleep and circadian trainees and expert faculty benefit from meaningful interactions with investigators from different research backgrounds, particularly those from biomedical research areas that are of high importance to the NIH/NHLBI. The research training activities of the 22 participating faculty emphasize transdisciplinary training in sleep and circadian physiology with research programs focused on cardiovascular, genetics/genomics, metabolomics, proteomics, biomarker development, bioinformatics, biostatistics, epidemiology, stress physiology, immunology, endocrinology, metabolism, obesity, diabetes, neuroscience, pediatrics, development, aging, psychiatry, and pulmonary and behavioral sleep medicine. Because our goal is to provide transdisciplinary and translational research career training, major program components of this T32 include the Department of Integrative Physiology, the Department of Psychology and Neuroscience, and the Institute for Behavioral Genetics at University of Colorado Boulder, and multiple clinical departments and divisions at University of Colorado School of Medicine Anschutz Medical Campus. The existing fruitful and collaborative environment is a strength of this training grant. Of the existing T32s at the University of Colorado, this would be the only one dedicated to transdisciplinary sleep and circadian science. Also, it would become the first sleep and circadian T32 in the Western United States. The specific aims of the training program are to recruit, select and retain outstanding trainees; promote inclusive excellence; provide high quality training, educational, and career development experiences to prepare trainees for research-intensive and research-related careers; shape tomorrow’s scientific leaders; foster rigorous and collaborative sleep and circadian science; ensure successful progress of trainees toward predetermined milestones defined in Individual Development Plans; enhance the mentoring skills of faculty through a formal mentoring training plan; ensure conscientious program evaluation; and expand the number of investigators conducting transdisciplinary sleep and circadian science. We request support for one pre-doctoral and one post-doctoral trainee in year 1, and two pre-doctoral and two post-doctoral trainees in years 2-5.