课题基金 / 基金详情

Characterizing molecular interactomes using TurboID

Characterizing molecular interactomes using TurboID
使用 TurboID 表征分子相互作用组
批准号：
10689616
负责人：
Mark Henderson
金额：
$14.62万
依托单位：
NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/10689616
关键词：
BiotinCollaborationsDiseaseExtramural ActivitiesGoalsInformaticsLabelLigaseModelingMolecularPharmaceutical ChemistryProcessResearchTranslationsUnited States National Institutes of HealthWorkdrug discoveryscreeningsmall moleculetherapeutic developmenttool

项目摘要

项目成果

Mark Henderson的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
During this period, the team has developed tools to explore new uses of TurboID as a proximity labeling tool to define interactomes. This collaborative team aims build on previous extramural research that has developed a promiscuous biotin ligase TurboID. The Early Translation Branch's (ETB) overall goal is to uncover new small molecule probes and catalyze the process of therapeutic development through a model of collaborative research. With each collaboration, NIH and extramural disease experts work with the ETBs drug discovery teams, leveraging their expertise in small molecule screening, medicinal chemistry and informatics.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
A Novel Cell-Based Assay to Identify Small Molecules for Galactocerebrosidase (GALC)
Identifying small molecules with selective toxicity towards muscle invasive prostate cancer cells
Evaluation of CD206 agonists in diabetic retinopathy
Identification of small molecules that improve trafficking of NLGN4X/Y for autism
海外基金