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Training Program in Substance Use and Use Disorders

药物使用和使用障碍培训计划

基本信息

批准号：
10618200
负责人：
Marcelo Andres Wood
金额：
$ 19.38万
依托单位：
UNIVERSITY OF CALIFORNIA-IRVINE
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-07-01 至 2025-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10618200
关键词：
Disease Training Programs substance use

项目摘要

Drug abuse and addiction represent major health issues both in the United States and worldwide. In the United States alone costs related to loss of work, crime, and health care exceed $700 billion a year. The field of addiction spans numerous disciplines including, but not limited to, medicine, psychiatry, neurobiology, pharmacology, public health, and law, illustrating the impact that drugs of abuse and addiction have on the human condition. We are currently experiencing an amazing growth of technologies yielding new insights into the biological effects of drugs of abuse and mechanisms for the development of dependence and addiction. At UC Irvine, the community of faculty and researchers studying the neurobiology of addiction is rapidly growing with support from the UC Irvine Center for Addiction Neuroscience (ICAN), a new NIDA P50 Center of Excellence called the Impact of Cannabinoids Across Lifespan (ICAL), and a new center focused on the medical and legislative challenges of legalized marijuana (Center for the Study of Cannabis). The goal of the proposed Training Program in Substance Use and Use Disorders is to train the next generation of innovative researchers in the field of addiction neuroscience by leveraging the exceptional strength in neuroscience at UCI, and the new centers focused on addiction research, to provide an educational and research experience that will position trainees as new leaders in the field. The training program is focused on predoctoral students and will provide the following: 1) a modern and interdisciplinary neurobiology of addiction course; 2) two courses related to cannabinoids and the endocannabinoid system that dovetail with the P50 ICAL research endeavors; 3) an annual addiction neuroscience symposium; 4) a training program annual retreat; 5) a scientific writing course; 6) a public speaking course provided by Activate to Captivate; 7) an addiction research seminar series; 8) a journal club; 9) instruction in methods for enhancing reproducibility; and 10) conference presentations. This will be the first training program on campus that is specifically focused on drugs of abuse and addiction. Together, the new centers focused on addiction bring together scientists and clinicians from over a dozen departments and four schools to address the grand challenges in this field, to train and educate the next generation of investigators and clinicians, and to disseminate important information to the public.

药物滥用和成瘾是美国和全世界的主要健康问题。在仅美国一年因失业、犯罪和医疗保健造成的损失就超过 7000 亿美元年。成瘾领域跨越许多学科，包括但不限于医学、精神病学、神经生物学、药理学、公共卫生和法律，说明药物的影响虐待和成瘾对人类状况有影响。我们目前正在经历惊人的增长的技术对滥用药物的生物效应和机制产生新的见解依赖性和成瘾性的发展。在加州大学欧文分校，教师和社区在加州大学欧文分校的支持下，研究成瘾神经生物学的研究人员正在迅速发展成瘾神经科学中心 (ICAN)，一个新的 NIDA P50 卓越中心，称为影响跨生命周期的大麻素 (ICAL)，以及一个专注于医疗和立法的新中心大麻合法化的挑战（大麻研究中心）。拟议的目标药物使用和使用障碍培训计划旨在培训下一代创新人才成瘾神经科学领域的研究人员利用独特的优势 UCI 的神经科学以及专注于成瘾研究的新中心，旨在提供教育和研究经验将使学员成为该领域的新领导者。培训计划是专注于博士前学生，将提供以下内容：1）现代和跨学科的成瘾神经生物学课程； 2）两门与大麻素和内源性大麻素相关的课程与 P50 ICAL 研究工作相吻合的系统； 3）年度成瘾神经科学座谈会; 4）年度静修培训计划； 5）科学写作课程； 6）公开演讲由Activate to Captivate 提供的课程； 7）成瘾研究系列研讨会； 8）期刊俱乐部； 9）提高再现性的方法指导； 10) 会议演讲。这将是第一个校园培训计划专门针对滥用药物和成瘾问题。这些专注于成瘾问题的新中心汇集了来自多个国家的科学家和临床医生。十几个部门和四所学校来应对这一领域的巨大挑战，进行培训和教育下一代研究人员和临床医生，并向民众。

项目成果

期刊论文数量（5）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Dopamine D2 receptor signaling in the brain modulates circadian liver metabolomic profiles.

DOI：
10.1073/pnas.2117113119
发表时间：
2022-03-15
期刊：
Proceedings of the National Academy of Sciences of the United States of America
影响因子：
11.1
作者：
Cervantes M;Lewis RG;Della-Fazia MA;Borrelli E;Sassone-Corsi P
通讯作者：
Sassone-Corsi P

The Brain's Reward System in Health and Disease.