Intergenerational Influences on Marriage, Contraception and Childbearing
Intergenerational Influences on Marriage, Contraception and Childbearing
批准号:
10604345
负责人:
William G. Axinn
金额:
$61.6万
依托单位国家:
美国
项目类别:
财政年份:
2020
资助国家:
美国
项目状态:
未结题
起止时间:
2020-06-15 至 2025-02-28
关键词:
AdultAgeArchivesBehaviorCellular PhoneCharacteristicsChildChild Mental DisordersChild WelfareChildhoodClinicalCommunitiesContraceptive UsageContraceptive methodsDNADataDiagnosticDiseaseDivorceEducationElderlyEventFamilyFamily StudyFathersGeneral PopulationGenerationsGeneticGenetic Predisposition to DiseaseGenetic ResearchGenetic studyHealthHigh PrevalenceHouseholdIncomeIndividualInfrastructureInternetInterviewInvestigationKnowledgeLinkLiving ArrangementMarriageMeasurementMeasuresMediatingMental HealthMental disordersModelingMothersNational Institute of Child Health and Human DevelopmentNational Institute of Mental HealthOutcomeParentsPersonal SatisfactionPersonsPlayPopulationPopulation GrowthPregnancyProcessRecording of previous eventsResearchResearch DesignRisk TakingRoleSalivaSamplingSeveritiesSexually Transmitted DiseasesShapesSocial SciencesStructureSurveysTelephone InterviewsVariantWorkchild bearingcommunity-level factordesignearly childhoodeffective interventionexperienceinnovationintergenerationalparental influenceparental rolepolygenic risk scoreprospectivesexsexual risk takingsubstance usetoolunintended pregnancy
中文摘要
点击翻译按钮获取中文摘要
英文摘要
PROJECT SUMMARY
Family formation processes, including marriage, contraception, and childbearing, are among the most im-
portant factors shaping the health and wellbeing of families and children. The substantial, long-term conse-
quences of the parental family for children's family formation outcomes are among the most well-documented
forces of change in the social sciences. However, a powerful factor has been overlooked—parental mental
health. Not only are mental disorders highly prevalent the world over, but parental mental disorders are known
to have powerful consequences for children, likely to shape their later-life family formation processes. We will
address this important gap in research by integrating parental mental disorders into intergenerational models of
family formation using a 24-year, prospective family panel study. To advance knowledge of these intergenera-
tional processes using these new measures, we aim to: (1) Generate the first estimates of the role of parental
mental disorders in shaping their children's subsequent marriage, contraception, and childbearing; (2) Use
DNA-based polygenic risk scores from mothers, fathers, and their children to assess omitted genetic variable
bias in these intergenerational models; and (3) Create and evaluate new prospective measures of sexual risk-
taking and substance use mechanisms likely to link parental mental disorders to their children's marriage, con-
traceptive use, and childbearing.
The results will provide three significant advances. One is the first general population investigation of the
intergenerational influence of parental mental disorders on children's marriage, contraception, and childbear-
ing. A second is the first study of the genetic contribution to the intergenerational influences of parental mental
disorders on family formation. To date nearly all population models of intergenerational influences on family
formation are forced to conclude that unobserved genetic similarities may account for observed associations.
We will introduce a new generation of intergenerational research—designs that integrate genetic propensities.
The third is a significant advance in our understanding of the role played by children's premarital sex, sex with-
out contraception, and substance use in linking parental factors to children's family formation, as these events
could mediate this relationship. These steps will significantly advance our understanding of the intergenera-
tional influences on the dynamics of marriage, contraception, and childbearing, all of which are crucial for
health and wellbeing.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
A New Population-scale Approach for the Study of Psychological Stress in the Transition to Adulthood
-
批准号:10493385
-
项目类别:
-
资助金额:$19.5万
-
财政年份:2021
-
负责人:William G. Axinn
-
依托单位:
A New Population-scale Approach for the Study of Psychological Stress in the Transition to Adulthood
-
批准号:10369850
-
项目类别:
-
资助金额:$23.4万
-
财政年份:2021
-
负责人:William G. Axinn
-
依托单位:
Intergenerational Influences on Marriage, Contraception and Childbearing
-
批准号:10183278
-
项目类别:
-
资助金额:$62.48万
-
财政年份:2020
-
负责人:William G. Axinn
-
依托单位:
Interdisciplinary Research Training Program for International Population Science
-
批准号:10186785
-
项目类别:
-
资助金额:$15.86万
-
财政年份:2020
-
负责人:William G. Axinn
-
依托单位:
Interdisciplinary Research Training Program for International Population Science
-
批准号:10612801
-
项目类别:
-
资助金额:$15.4万
-
财政年份:2020
-
负责人:William G. Axinn
-
依托单位:
Interdisciplinary Research Training Program for International Population Science
-
批准号:10400067
-
项目类别:
-
资助金额:$15.58万
-
财政年份:2020
-
负责人:William G. Axinn
-
依托单位:
Intergenerational Influences on Marriage, Contraception and Childbearing
-
批准号:10366002
-
项目类别:
-
资助金额:$62.33万
-
财政年份:2020
-
负责人:William G. Axinn
-
依托单位:
Archiving and Documenting Child Health and Human Development Data Sets
-
批准号:9543523
-
项目类别:
-
资助金额:$7.8万
-
财政年份:2017
-
负责人:William G. Axinn
-
依托单位:
Genes, Environment, Family and Mental Health
-
批准号:9127827
-
项目类别:
-
资助金额:$29.97万
-
财政年份:2015
-
负责人:William G. Axinn
-
依托单位:
Reciprocal Relations between Population and Environment
-
批准号:7900948
-
项目类别:
-
资助金额:$51.02万
-
财政年份:2009
-
负责人:William G. Axinn
-
依托单位:
Reciprocal Relations between Population and Environment
-
批准号:7527197
-
项目类别:
-
资助金额:$52.96万
-
财政年份:2009
-
负责人:William G. Axinn
-
依托单位:
Electronic Journal Data Collection Technologies for Interdisciplinary Research
-
批准号:7501425
-
项目类别:
-
资助金额:$29.43万
-
财政年份:2007
-
负责人:William G. Axinn
-
依托单位:
Electronic Journal Data Collection Technologies for Interdisciplinary Research
-
批准号:7893797
-
项目类别:
-
资助金额:$29.14万
-
财政年份:2007
-
负责人:William G. Axinn
-
依托单位:
Electronic Journal Data Collection Technologies for Interdisciplinary Research
-
批准号:7363319
-
项目类别:
-
资助金额:$30.0万
-
财政年份:2007
-
负责人:William G. Axinn
-
依托单位:
Electronic Journal Data Collection Technologies for Interdisciplinary Research
-
批准号:7660387
-
项目类别:
-
资助金额:$29.43万
-
财政年份:2007
-
负责人:William G. Axinn
-
依托单位:
Development Core
-
批准号:10457696
-
项目类别:
-
资助金额:$29.68万
-
财政年份:2001
-
负责人:William G. Axinn
-
依托单位:
Development Core
-
批准号:10226830
-
项目类别:
-
资助金额:$25.27万
-
财政年份:2001
-
负责人:William G. Axinn
-
依托单位:
Development Core
-
批准号:10621371
-
项目类别:
-
资助金额:$29.68万
-
财政年份:2001
-
负责人:William G. Axinn
-
依托单位:
INTERGENERATIONAL PANEL STUDY OF PARENTS AND CHILDREN
-
批准号:2857468
-
项目类别:
-
资助金额:$0.61万
-
财政年份:1997
-
负责人:William G. Axinn
-
依托单位:
INTERGENERATIONAL PANEL STUDY OF PARENTS AND CHILDREN
-
批准号:2634966
-
项目类别:
-
资助金额:$1.92万
-
财政年份:1997
-
负责人:William G. Axinn
-
依托单位:
国内基金
海外基金
登录
查看更多内容
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
-
批准号:JCZRLH202601523
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:
-
依托单位:
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
-
批准号:JCZRQN202500010
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:
-
依托单位:
对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
-
批准号:2025JJ70209
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:雷芬芳
-
依托单位:
AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
-
批准号:--
-
项目类别:面上项目
-
资助金额:--
-
批准年份:2024
-
负责人:万荣
-
依托单位:
甜茶抑制AGE-RAGE通路增强突触可塑性改善小鼠抑郁样行为
-
批准号:2023JJ50274
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2023
-
负责人:贺志明
-
依托单位:
蒙药额尔敦-乌日勒基础方调控AGE-RAGE信号通路改善术后认知功能障碍研究
-
批准号:--
-
项目类别:地区科学基金项目
-
资助金额:33万元
-
批准年份:2022
-
负责人:都义日
-
依托单位:
补肾健脾祛瘀方调控AGE/RAGE信号通路在再生障碍性贫血骨髓间充质干细胞功能受损的作用与机制研究
-
批准号:--
-
项目类别:面上项目
-
资助金额:52万元
-
批准年份:2022
-
负责人:叶宝东
-
依托单位:
LncRNA GAS5在2型糖尿病动脉粥样硬化中对AGE-RAGE 信号通路上相关基因的调控作用及机制研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:10.0万元
-
批准年份:2022
-
负责人:于海兵
-
依托单位:
围绕GLP1-Arginine-AGE/RAGE轴构建探针组学方法探索大柴胡汤异病同治的效应机制
-
批准号:81973577
-
项目类别:面上项目
-
资助金额:55.0万元
-
批准年份:2019
-
负责人:辛贵忠
-
依托单位:
AGE/RAGE通路microRNA编码基因多态性与2型糖尿病并发冠心病的关联研究
-
批准号:81602908
-
项目类别:青年科学基金项目
-
资助金额:18.0万元
-
批准年份:2016
-
负责人:刘括
-
依托单位: