CANCER CONTROL RESEARCH PROGRAM

癌症控制计划的使命是促进合作研究，以减少癌症风险， 降低死亡率，提高癌症患者的生活质量。该计划促进三个方面的研究 专题领域：（1）预防/减少风险;（2）筛查/早期发现;（3）生活质量/ 在乎跨领域主题包括交流研究、翻译/传播/采用， 一个发展中的健康服务研究主题。该计划由来自10个国家的21名成员组成 各部门占总资金的660万美元，其中400万美元来自NCI。这群 研究人员在本资助期内发表了268篇同行评审的手稿，其中88篇 (33%）是与其他方案的联合出版物，表明方案间的高度合作。 在合作方面，自上次审查以来，此类活动大幅增加。此外，79名（29%） 出版物是方案内的，反映了我们21个方案成员之间的合作。 方案重点包括所有三个专题领域的新发现。预防研究人员发表了 并传播了一项旨在促进青少年防晒行为的试验结果。他们有 发表的一项研究表明，在电影中接触吸烟与青少年吸烟之间存在联系， 这项研究为减少电影吸烟的公共卫生运动奠定了基础。筛选 研究人员领导了美国5个乳房X光检查登记处之一， 采取干预措施，促进初级保健中的癌症筛查。项目成员提出尖锐的问题 关于目前癌症筛查方法的效用，考虑到过度诊断偏见等问题。 生活质量研究人员发表了关于癌症治疗对癌症患者的不良影响的新发现。 认知功能，也表明APOE的E14等位基因与此相关的风险较高， 并发症通信研究人员正在设计有效的方法来讨论治疗和药物 与患者一起做出决定，并与FDA合作传播这些决定。我们正在建设能力， 通过招聘和指导计划进行通信和卫生服务提供方面的研究。 项目负责人主持成员之间和项目之间的定期会议，以促进合作， 确保指导年轻的研究人员，成员参加T32博士学位。健康培训计划 服务研究。展望未来，该计划预计将增加招聘和继续扩大， 优势领域，包括研究媒体对癌症风险行为的影响，乳房X光检查 研究和传播护理实践系统，以支持癌症筛查。

The mission of the Cancer Control Program is to promote collaborative research to reduce cancer risk and mortality and to enhance the quality of life of cancer patients. The Program fosters research across three thematic areas: (1) Prevention/risk reduction; (2) Screening/early detection; and (3) Quality of life/quality of care. Cross-cutting themes include research on communications, and translation/dissemination/adoption, with a developing health services research theme. The Program consists of 21 members from 10 departments accounting for $6.6 million in total funding, of which $4 million is from the NCI. This group of investigators has published 268 peer-reviewed manuscripts during the current funding period, of which 88 (33%) were joint publications with other programs, indicating a high degree of inter-programmatic collaboration, a substantial increase in such activity since the last review. In addition, 79 (29%) of the publications were intra-programmatic, reflecting collaborative work among our 21 program members. Program highlights include novel findings in all three thematic areas. Prevention researchers have published and disseminated findings from a trial to promote sun-safe behaviors among adolescents. They have published research showing a relation between exposure to smoking in movies and adolescent smoking, research that forms the basis for a public health campaign to reduce movie smoking depictions. Screening researchers lead one of 5 mammography registries in the U.S. and are disseminating successful interventions to promote cancer screening in primary care. Program members ask penetrating questions about the utility of current approaches to cancer screening, given issues such as over-diagnosis bias. Quality-of-life researchers have published novel findings on the adverse effects of cancer treatments on cognitive function, showing also that the epsilon 4 allele of APOE is associated with higher risk for this complication. Communications researchers are devising effective ways to discuss treatment and medication decisions with patients and working with the FDA to disseminate them. We are building our capacity to do research in communications and health services delivery through a recruitment and mentorship program. Program leaders host regular meetings among members and across programs to foster collaboration and ensure mentorship of young investigators, and members participate in a T32 Ph.D. training program in health services research. Going forward, the Program anticipates additional recruitment and continued expansion in areas of strength, including research into media influences on cancer risk behaviors, mammography research, and dissemination of practice systems of care to support cancer screening.