CANCER CONTROL RESEARCH PROGRAM

癌症控制计划的使命是促进合作研究，以降低癌症风险和 降低死亡率，提高癌症患者的生活质量。该计划促进了三个领域的研究 专题领域：(1)预防/减少风险；(2)筛查/早期发现；(3)生活质量/生活质量 关心。交叉主题包括关于传播的研究和翻译/传播/采用， 有一个发展中的卫生服务研究主题。该计划由来自10个国家的21名成员组成 各部门的资金总额为660万美元，其中400万美元来自NCI。这群人 调查人员在当前资助期间发表了268篇同行评议的手稿，其中88篇 (33%)是与其他计划联合出版的，表明计划间的高度交叉 自上次审查以来，这类活动大幅增加。此外，79名(29%) 出版物是方案内的，反映了我们21个方案成员之间的协作工作。 计划的亮点包括在所有三个主题领域的新发现。预防研究人员发表了 并传播了一项在青少年中推广防晒行为的试验结果。他们有 发表的研究表明，接触电影中的吸烟与青少年吸烟之间存在关系， 这项研究构成了一项公共卫生运动的基础，以减少电影中吸烟的描述。筛选 研究人员领导着美国5个乳房X光检查登记之一，并正在传播成功的 在初级保健中促进癌症筛查的干预措施。计划成员提出尖锐的问题 关于目前癌症筛查方法的效用，考虑到过度诊断偏见等问题。 生活质量研究人员发表了关于癌症治疗的不良影响的新发现 认知功能，也表明apoE的epsilon 4等位基因与此相关的风险更高。 很复杂。通信研究人员正在设计有效的方法来讨论治疗和药物治疗 与患者一起做出决定，并与FDA合作传播这些决定。我们正在建设我们的能力，以做到 通过招聘和指导计划在通信和卫生服务交付方面进行研究。 计划负责人定期主持成员之间和跨计划的会议，以促进协作和 确保年轻研究人员的指导，成员参加T32博士健康培训计划 服务研究。展望未来，该计划预计将在#年进行更多招聘并继续扩大规模 优势领域，包括媒体对癌症危险行为的影响研究，乳房X光检查 研究和传播支持癌症筛查的实践护理系统。

The mission of the Cancer Control Program is to promote collaborative research to reduce cancer risk and mortality and to enhance the quality of life of cancer patients. The Program fosters research across three thematic areas: (1) Prevention/risk reduction; (2) Screening/early detection; and (3) Quality of life/quality of care. Cross-cutting themes include research on communications, and translation/dissemination/adoption, with a developing health services research theme. The Program consists of 21 members from 10 departments accounting for $6.6 million in total funding, of which $4 million is from the NCI. This group of investigators has published 268 peer-reviewed manuscripts during the current funding period, of which 88 (33%) were joint publications with other programs, indicating a high degree of inter-programmatic collaboration, a substantial increase in such activity since the last review. In addition, 79 (29%) of the publications were intra-programmatic, reflecting collaborative work among our 21 program members. Program highlights include novel findings in all three thematic areas. Prevention researchers have published and disseminated findings from a trial to promote sun-safe behaviors among adolescents. They have published research showing a relation between exposure to smoking in movies and adolescent smoking, research that forms the basis for a public health campaign to reduce movie smoking depictions. Screening researchers lead one of 5 mammography registries in the U.S. and are disseminating successful interventions to promote cancer screening in primary care. Program members ask penetrating questions about the utility of current approaches to cancer screening, given issues such as over-diagnosis bias. Quality-of-life researchers have published novel findings on the adverse effects of cancer treatments on cognitive function, showing also that the epsilon 4 allele of APOE is associated with higher risk for this complication. Communications researchers are devising effective ways to discuss treatment and medication decisions with patients and working with the FDA to disseminate them. We are building our capacity to do research in communications and health services delivery through a recruitment and mentorship program. Program leaders host regular meetings among members and across programs to foster collaboration and ensure mentorship of young investigators, and members participate in a T32 Ph.D. training program in health services research. Going forward, the Program anticipates additional recruitment and continued expansion in areas of strength, including research into media influences on cancer risk behaviors, mammography research, and dissemination of practice systems of care to support cancer screening.