Training Program in Biomedical Imaging and Informational Sciences

描述(由申请人提供)： 对临床相关影像科学的量化基础科学家的培训日益重要。 优秀的成像科学在宾夕法尼亚大学的多所学校都有很好的表现，但在培训方面的努力没有正式的整合，也没有正式的临床部分，直到最近生物医学成像和信息科学培训计划的创建。该计划于2006年在HHMI-NIBIB接口倡议的支持下建立，代表着由医学与工程研究所和放射科与多所学校的许多其他部门合作领导的合作伙伴关系。我们的前提是，定量成像科学中最成功的研究和技术是那些整合了临床相关性、数学严谨性和工程技巧的研究和技术。因此，新的项目在接受分析科学的同时，也包含了强大的临床风险。其目标是开发一种新的跨学科培训，确保学生达到一定程度的整合，使他们能够成为假设驱动的、专注于临床的生物医学成像研究的下一代领导者。一个名为博士基础的新课程将提供为期18个月的生物医学核心教学要素和生物医学成像基础科学教育的垂直整合，包括四个组成部分，其中两个是基础组成部分，其次是综合组成部分和专业组成部分。在第一门，生物医学基础(2门课程)中，学生将参加医学生课程修改后的模块1和模块2，该模块教授医学核心原理(包括大体解剖学)和为期12个月的器官系统医学、综合系统和疾病序列。此外，还将开设4门新的影像科学基础课程：分子成像、生物医学图像分析、成像基础技术和医学成像与测量数学。第三部分是综合单元：放射学基础和生物医学影像科学研讨会课程。第四个组成部分是专业培训：负责任的研究行为、教学实践、以患者为中心的研究培训、通过参与教职员工的实验室进行的研究生存。为了确保论文研究以转化医学为导向，通过解决离散的临床问题，受训人员将由临床和基础科学学院的成员共同建议。

DESCRIPTION (provided by applicant): The training of quantitative basic scientists in clinically-related imaging science is increasingly important. Excellent imaging sciences are well represented at Penn in multiple schools, but no formal integration of efforts in training existed, nor was there a formal clinical component to the training until the recent creation of the Training Program in Biomedical Imaging and Informational Sciences. Established in 2006 under the auspices of the HHMI-NIBIB Interfaces Initiative, the program represents a partnership led by the Institute for Medicine and Engineering and the Department of Radiology in collaboration with many other departments across multiple Schools. Our premise is that the most successful research and technologies in quantitative imaging science are those that integrate clinical relevance, mathematical rigor, and engineering finesse. Accordingly, the new program embraces strong clinical exposure alongside analytical science. The objective is to develop a new kind of interdisciplinary training by ensuring that students attain a level of integration that would allow them to become the next generation of leaders in hypothesis-driven, clinically focused biomedical imaging research. A new curriculum, the doctoral foundation, will provide 18 months of vertical integration of the core didactic elements of biomedicine and basic science education in biomedical imaging through 4 components, two of them Foundational, followed by Integrative and Professional components. In the first, Foundations in Biomedical Science (2 courses), students will participate in modified modules 1 and 2 of the medical student curriculum that teaches the Core Principles of Medicine (including Gross Anatomy) and a 12-month sequence of organ systems medicine, Integrative Systems and Diseases. This will be complemented by 4 new courses in Foundations of Image Science: Molecular Imaging, Biomedical Image Analysis, Fundamental Techniques of Imaging, and Mathematics of Medical Imaging & Measurements. The third component is an Integrative Module: Foundations of Radiology and a Biomedical Image Sciences Seminar course. The fourth component is Professional Training: Responsible Conduct of Research, Teaching Practicum, Patient-Oriented Research Training, Research 'Survival' rough the laboratories of the participating faculty. To ensure that the thesis research is directed to translational medicine through the solution of discrete clinical problems, trainees will be co-advised by members f the clinical and basic science faculty.