Micro CT image processing for high contrast images

高对比度图像的显微 CT 图像处理

• 批准号: 523215-2018
• 负责人: Tamimi, Faleh
• 金额: $ 1.82万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=666460
• 关键词: Micro; CT; image; processing; contrast

Trikon Technologies (Montreal) specializes in nondestructive testing and 3D imaging, and is interested in**expansion from engineering and materials sciences towards life sciences. Effective analysis of biological**objects requires special expertise in bio-image processing because of their high structural complexity and more**delicate nature of such objects. This project aims to enrich the company's portfolio to include bio-imaging.**Using advanced instrumentation at Trikon, academic partners at McGill University will analyze trabecular**bone texture that reflects functional adaptation to biomechanical requirements. A series of human bones that**have been naturally subjected to different loading conditions will be scanned using X-ray tomography at the**company's facilities. A sequence of image processing steps will be established and optimized (i.e., filtering,**segmentation, structure shape and topology analysis, machine learning-based feature extraction and**quantification). This sequence of analysis will be unified into an automated protocol (macro); automation of**processing routines by writing macros is important in reducing hands-on time for staff, optimizing**computational processing time, and guaranteeing reproducibility. This work on bone texture analysis will**serve as a training platform for acquiring expertise by Trikon applications specialists. Optimized and**automated image processing protocols resulting in quantitative analysis of the data will become a unique**company capability. Future applications of this versatile characterization protocol include (but are not limited**to) physical anthropology, archaeology, forensics, zoology, botany, orthopaedic medicine and dentistry, and**even civil engineering for development of biomimetic materials. Trikon specialists will expand their industrial**niche by investing in high-end technology and data processing that will help to define determinants of skeletal**adaptation by the academic partner.

Trikon Technologies（蒙特利尔）专门从事无损检测和3D成像，并对从工程和材料科学向生命科学的扩展感兴趣。由于生物图像的结构复杂性和更微妙的性质，对生物图像的有效分析需要生物图像处理方面的专门知识。该项目旨在丰富公司的产品组合，包括生物成像。**使用Trikon的先进仪器，麦吉尔大学的学术合作伙伴将分析反映生物力学要求的功能适应性骨小梁纹理。在 ** 公司的设施中，将使用X射线断层扫描技术对一系列自然经受不同载荷条件的人骨进行扫描。将建立和优化图像处理步骤的序列（即，滤波、** 分割、结构形状和拓扑分析、基于机器学习的特征提取和 ** 量化）。该分析序列将统一到自动化方案（宏）中;通过编写宏来实现 ** 处理例程的自动化对于减少工作人员的动手时间、优化 ** 计算处理时间和保证再现性非常重要。这项关于骨骼纹理分析的工作将 ** 作为Trikon应用专家获得专业知识的培训平台。优化和 ** 自动化的图像处理协议导致数据的定量分析将成为一个独特的 ** 公司的能力。这种多功能表征协议的未来应用包括（但不限于）体质人类学，考古学，法医学，动物学，植物学，矫形医学和牙科，甚至是用于仿生材料开发的土木工程。Trikon专家将通过投资高端技术和数据处理来扩大其工业利基，这将有助于学术合作伙伴确定骨骼适应的决定因素。