Micro CT image processing for high contrast images

Trikon Technologies(蒙特利尔)专注于无损检测和3D成像，并对**从工程和材料科学向生命科学扩展感兴趣。对生物物体的有效分析需要生物图像处理方面的专门知识，因为它们的结构高度复杂，而且这类物体的性质更精致。该项目旨在丰富公司的产品组合，包括生物成像。**利用Trikon的先进仪器，麦吉尔大学的学术合作伙伴将分析反映功能适应生物力学要求的骨小梁纹理。一系列自然承受不同载荷条件的人类骨骼将在该公司的设施中使用X射线断层扫描进行扫描。将建立和优化一系列图像处理步骤(即过滤、**分割、结构形状和拓扑分析、基于机器学习的特征提取和**量化)。这一分析序列将统一到一个自动化协议(宏)中；通过编写宏实现**处理例程的自动化对于减少工作人员的实际操作时间、优化**计算处理时间以及保证重复性非常重要。这项关于骨骼纹理分析的工作将**作为Trikon应用专家获取专业知识的培训平台。优化的和**自动化的图像处理协议将导致数据的定量分析，这将成为**公司的一项独特能力。这一通用的表征协议的未来应用包括(但不限于**)物理人类学、考古学、法医学、动物学、植物学、骨科医学和牙科，以及**甚至用于开发仿生材料的土木工程。Trikon专家将通过投资高端技术和数据处理来扩大他们的行业**利基市场，这些技术和数据处理将帮助学术合作伙伴确定骨骼适应的决定因素。

Trikon Technologies (Montreal) specializes in nondestructive testing and 3D imaging, and is interested in**expansion from engineering and materials sciences towards life sciences. Effective analysis of biological**objects requires special expertise in bio-image processing because of their high structural complexity and more**delicate nature of such objects. This project aims to enrich the company's portfolio to include bio-imaging.**Using advanced instrumentation at Trikon, academic partners at McGill University will analyze trabecular**bone texture that reflects functional adaptation to biomechanical requirements. A series of human bones that**have been naturally subjected to different loading conditions will be scanned using X-ray tomography at the**company's facilities. A sequence of image processing steps will be established and optimized (i.e., filtering,**segmentation, structure shape and topology analysis, machine learning-based feature extraction and**quantification). This sequence of analysis will be unified into an automated protocol (macro); automation of**processing routines by writing macros is important in reducing hands-on time for staff, optimizing**computational processing time, and guaranteeing reproducibility. This work on bone texture analysis will**serve as a training platform for acquiring expertise by Trikon applications specialists. Optimized and**automated image processing protocols resulting in quantitative analysis of the data will become a unique**company capability. Future applications of this versatile characterization protocol include (but are not limited**to) physical anthropology, archaeology, forensics, zoology, botany, orthopaedic medicine and dentistry, and**even civil engineering for development of biomimetic materials. Trikon specialists will expand their industrial**niche by investing in high-end technology and data processing that will help to define determinants of skeletal**adaptation by the academic partner.