Acquisition of 500 mHz NMR Instrument

为先进材料中心（CAM）提供资金，为大学内50多名教职员工和研究生的研究项目购买500 mhz核磁共振仪器。该仪器的可用性将使中心能够扩大和发展材料方面的大量跨学科研究。目前，该机构没有进行500兆赫研究的能力。正在进行的研究项目包括：1)天然聚-羟基烷酸酯的合成类似物；2)立体化学和重复单元序列分析；3)刚性棒状选择性壳聚糖衍生物的表征；4)生物降解产物的表征；5)发酵反应及产物表征；6)两亲性阳离子-阴离子聚合物的可逆缔合/凝胶化；7)分子内和分子间离子相互作用的相对强度；8)通过活性阳离子聚合得到定义良好的接枝和功能聚合物；活性阳离子聚合中卤化引发反应；10)噻吩生物素化共聚物和非线性光学发色团取代噻吩共聚物的合成与表征，它们是用于单层、光伏和生物传感器的前驱体；用于二阶和三阶非线性光学的新型聚二乙炔的合成与表征；12) NLO应用的客-主、溶胶-凝胶和互穿聚合物网络（IPN）体系的合成和表征；聚乙炔的核磁共振研究；14)硒和碲化合物的化学位移、偶联常数和分子结构的研究。为先进材料中心（CAM）提供资金，为大学内50多名教职员工和研究生的研究项目购买500 mhz核磁共振仪器。该仪器的可用性将使中心能够扩大和发展大量的材料跨学科研究。目前，该机构没有进行500兆赫研究的能力。高场仪器较大的化学位移色散有利于材料的表征，特别是聚合物立体化学，测序和生物大分子。这些信息对于确定聚合和降解以及大分子相互作用的机制非常有价值。此外，灵敏度提高四倍将允许研究低灵敏度核和/或稀释自旋系统，这些系统目前要么无法获得，要么只能通过制备同位素富集材料来获得。

Funds are provided to The Center for Advanced Materials (CAM) to acquire a 500-MHz NMR instrument for research programs of more than 50 faculty, staff and graduate students within the University. The availability of this instrument will allow the Center to expand and develop substantial interdisciplinary research in materials. Currently, no capability for 500-MHz studies exists at the institution. Research initiatives just underway include studies of: 1)synthetic analogues of natural poly(beta- hydroxyalkanoates); 2) stereochemical and repeat unit sequence analysis; 3) characterization of rigid-rod like site-selective Chitosan derivatives; 4) characterization of biodegradation products; 5) characterization of fermentation reactions and products; 6) reversible association/gelation of amphiphilic cation-anion polymers; 7)relative strength of intraand intermolecular ionic interactions; 8) well-defined blockgraft- and functional polymers by living cationic polymerization; 9)initiation via haloboration in living cationic polymerization; 10) syntheses and characterization of biotinylated copolymers of thiophene and nonlinear optical chromophore substituted copolymers of thiophene which are precursors for monolayer, photovoltaic and biosensor applications; 11) syntheses and characterization of novel polydiacetylenes for second and third order nonlinear optical applications; 12) syntheses and characterization of guest-host, sol-gel, and interpenetrating polymer network(IPN) systems for NLO applications; 13) NMR studies of polyacetylenes; 14) and studies of chemical shifts, coupling constant, and molecular structures of selenium and tellurium compounds. Funds are provided to The Center for Advanced Materials (CAM) to acquire a 500-MHz NMR instrument for research programs of more than 50 faculty, staff and graduate students within the University. The availability of this instrument will allow the Center to expand and develop substantial interdisciplinary research in m aterials. Currently, no capability for 500-MHz studies exists at the institution. The greater chemical shift dispersion of the high field instrument is advantageous for characterization of materials, particularly polymer stereochemistry, sequencing and biological macromolecules. Such information is extremely valuable for determining mechanisms of polymerization and degradation and macromolecular interactions. In addition, the four-fold gain in sensitivity will permit studies of low sensitivity nuclei and/or dilute spin systems that are currently either inaccessible or accessible only through the preparation of isotopically enriched materials.