NMR Facility Upgrade

这份来自学术研究基础设施（ARI）计划的奖励将帮助加州大学欧文分校化学系升级现有的500 MHz和300 MHz核磁共振。这种设备将加强若干领域的研究，包括：(1)中枢神经系统的信号传导机制(2)单分散二氧化硅负载催化剂的新模型(3)多肽b片的形成策略(4)具有高立体和对映控制的复杂分子的高效组装的新反应和策略(5)多烯大环内酯类抗生素(6)合成方法/天然产物合成和聚合物合成/材料化学(7)含吲哚环偶联的化合物的研究(8)硅环丙烷的新反应。核磁共振（NMR）波谱是化学家用来阐明分子结构的最有力的工具。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。获得最先进的核磁共振光谱是必不可少的化学家谁正在进行前沿研究。这些核磁共振研究的结果在聚合物、催化和生物学等领域是有用的。

9601658 Chamberlin University of California Irvine This award from the Academic Research Infrastructure (ARI) Program will assist the Department of Chemistry at the University of California at Irvine upgrade the existing 500 MHz and 300 MHz NMRs. This equipment will enhance research in a number of areas including the following: (1) signaling mechanisms in the central nervous system (2) new models for monodisperse silica-supported catalysts (3) strategies for the formation of peptide b-sheets (4) new reactions and strategies that allow the efficient assembling of complex molecules with high stereo- and enantiocontrol (5) polyene macrolide antibiotics (6) synthetic methodology/natural product synthesis and polymer syntheses/materials chemistry (7) research of compounds which contain indole rings coupled at the 2 position, and (8) new reactions of silacyclopropanes. Nuclear Magnetic Resonance (NMR) spectroscopy is the most powerful tool available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometry is essential to chemists who are carrying out frontier research. The results from these NMR studies are useful in the areas such as polymers, catalysis, and in biology.