Studies in Organized Media

这个更新项目由分析和表面化学项目支持，重点研究有组织介质的基础研究，包括环糊精、聚合环糊精和树状大分子，用于分析分离，特别是毛细管电泳。一套分子光谱技术，包括荧光、吸光度和圆二色性，将在这些研究中使用，并将辅以停止流动动力学方法。在这个为期三年的项目中，华纳教授和他在路易斯安那州立大学的学生，以及巴吞鲁日南方大学的罗伯特·古登教授的合作投入，将追求更好地理解分离科学中使用的有组织媒体的目标。有组织的介质提供了分析物可以从水溶液进入的第二相。分析物在水溶液和有组织介质之间的这种分配在分离科学领域有广泛的应用。有组织的介质可以作为一个伪固定相，并作为一种方式赋予溶解性，否则不溶的分析物在水溶液中。在这个项目中，将合成有组织的介质，特别是环糊精和树状大分子，并评价它们在分析分离具有环境意义的分析物方面的适用性。

This renewal project, supported in the Analytical and Surface Chemistry Program, focusses on fundamental studies of organized media, including cyclodextrins, polymeric cyclodextrins and dendrimers, for application in analytical separations with particular focus on capillary electrophoresis. A suite of molecular spectroscopic techniques, including fluorescence, absorbance, and circular dichroism, will be utilized in these studies and will be complemented by stopped-flow kinetic methods. During the tenure of this three year project, Professor Warner and his students at Louisiana State University, with collaborative input from Professor Robert Gooden of Southern University - Baton Rouge, will pursue the objective of better understanding organized media for use in separation science. Organized media provide a second phase into which analytes can move from aqueous solution. This partitioning of analytes between aqueous solution and the organized media has wide application in the field of separation science. The organized media can serve as a pseudo-stationary phase and as a way of imparting solubility to otherwise insoluble analytes in aqueous solution. In this project, organized media, particularly cyclodextrins and dendrimers, will be synthesized and their applicability in analytical separations of environmentally significant analytes will be evaluated.