2001 CSHL Conference on Eukaryotic mRNA Processing to be held August 22-26, 2001, Cold Spring Harbor New York

冷泉港实验室会议“真核mRNA加工”，将于2001年8月22日至26日举行，将召集科学家研究mRNA加工、运输和周转的各个方面。最近在这些领域取得了重大进展，会议将是一个及时的活动，讨论最新的未发表的结果和交换意见，从而促进这个迅速发展的领域的新发展。2001年会议是该会议的第三次会议，每隔一年在冷泉港实验室举行一次。最近的一次会议于1999年8月25日至29日举行，吸引了277名国际科学家，他们正在积极研究真核细胞中信使RNA成熟的各个方面，使用遗传，生化，分子和细胞生物学方法。与之前的会议一样，主要焦点将集中在mRNA成熟过程中的核事件，特别是mRNA剪接和聚腺苷化，但现在的范围将扩大到mRNA的历史对其最终生物学命运的影响。会议形式将包括七次全体会议和三次海报会议。全体会议的发言人将根据提交的摘要选择，这将鼓励年轻科学家积极参与。主要内容包括mRNA剪接和3'端加工的催化机制；选择性剪接和聚腺苷酸化对基因表达的发育和细胞类型特异性调控snRNP和hnRNP粒子的结构和功能；加工机械的装配；mRNA转运和周转；RNA加工反应的定位和动力学。信使RNA （mRNA）是一种分子，它以细胞可用的形式携带基因编码的信息。不同类型的mRNA的加工使细胞能够根据细胞的需要调节其使用。mRNA的适当加工对其功能至关重要。这次会议将有助于传播关于这一重要议题的最新研究成果，并将刺激和促进进一步的进展。该奖项将使在美国工作的研究生、博士后研究员和年轻研究人员能够参加会议。

The Cold Spring Harbor Laboratory Conference "Eukaryotic mRNA Processing", to be held August 22 - 26, 2001, will convene scientists studying various aspects of mRNA processing, transport and turn-over. Major advances have recently been made in these areas, and the conference will be a timely event for discussing the latest unpublished results and exchanging ideas, thereby fostering new developments in this rapidly moving field. The 2001 conference is the third meeting of this conference, which is held every other year at Cold Spring Harbor Laboratory. The most recent meeting was held on August 25-29, 1999, and attracted internationally 277 scientists who are actively investigating various aspects of messenger RNA maturation in eukaryotic cells, using genetic, biochemical, molecular, and cell biological approaches. As in the previous meetings, a major focus will be on nuclear events in mRNA maturation, particularly mRNA splicing and polyadenylation, but the scope will now be expanded to encompass the impact of the history of an mRNA on its ultimate biological fate. The meeting format will consist of seven plenary sessions and three poster sessions. Speakers in the plenary sessions will be selected on the basis of the submitted abstracts, which will encourage active participation by junior scientists. The main topics covered will include catalytic mechanisms of mRNA splicing and 3'-end processing; developmental and cell-type specificregulation of gene expression by alternative splicing and polyadenylation; structure and function of snRNP and hnRNP particles; assembly of the processing machineries; mRNA transport and turnover; and localization and dynamics of RNA processing reactions. A messenger RNA (mRNA) is a molecule that carries the information encoded by a gene in a form that is useable by the cell. Various types of processing of mRNA's enable cells to regulate their use according to the cells' needs. Proper processing of mRNA's is essential for their functioning. This meeting will help disseminate current research findings on this vital topic and will stimulate and facilitate further advances. This award will enable graduate students, postdoctoral fellows, and young investigators working in the United States to attend the meeting.