Acquisition of a 600 MHz NMR Spectrometer

有了化学研究仪器和设施(CRIF)计划的这一奖项，加州大学圣克鲁斯分校的化学系将获得一台600 MHz核磁共振光谱仪。该设备将使研究人员能够在多个领域开展研究，包括a)生物有机化合物混合物的表征；b)蛋白质信号和折叠的作用；c)自由基试剂；d)新的手性合成工具；e)金属酶和治疗中的金属离子；f)脂肪氧合酶中活性部位铁的动力学。核磁共振波谱是化学家用来阐明分子结构的最有力的工具之一。它被用来识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。这些核磁共振研究的结果将对合成有机化学和生物化学产生影响。

With this award from the Chemistry Research Instrumentation and Facilities (CRIF) Program, the Department of Chemistry at the University of California in Santa Cruz will acquire a 600 MHz NMR Spectrometer. This equipment will enable researchers to carry out research in a number of areas, including a) characterization of bioorganic compound mixtures; b) the role of protein signaling and folding; c) radical reagents; d) new chiral synthesis tools; e) metal ions in metalloenzymes and therapeutics; and f) dynamics of active site iron in lipoxygenases. Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organic chemistry and biochemistry.