MRI: Acquisition of High-sensitivity NMR Capabilities for the University of Oregon Magnetic Resonance Facility

该奖项由2009年《美国复苏与再投资法案》(Public Law 111-5)提供资金支持，迈克尔·黑利(Michael Haley)及其同事Victoria J.DeRose、Darren W.Johnson、刘诗媛和David R.Tyler将利用重大研究仪器(MRI)项目的这一奖项升级两台核磁共振光谱仪。所要求的仪器包括一个新的控制台，用于600 MHz核磁共振系统的碳-13优化低温探头和可调宽带探头，以及用于500 MHz核磁共振光谱仪的可调宽带探头。该仪器将用于研究1)笼子中的溶剂效应，2)基于苯乙炔支架的富碳网络和材料，3)RNA结构生物学，4)碳-硼-氮杂环作为储氢材料的发展，5)多金属纳米团簇和主族超分子化学。核磁共振光谱是化学家可用于阐明分子结构的最强大的工具之一。它被用来识别未知物质，表征分子内原子的特定排列，并研究分子之间相互作用的动力学。对于正在进行前沿研究的化学家来说，获得最先进的核磁共振光谱仪是必不可少的。这些核磁共振研究的结果将对合成有机/无机化学、生物化学和环境产生影响。这些仪器将是教学和研究不可或缺的一部分。

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).With this award from the Major Research Instrumentation (MRI) program, Michael Haley and colleagues Victoria J. DeRose, Darren W. Johnson, Shih-Yuan Liu and David R. Tyler will upgrade two NMR spectrometers. The requested instrumentation includes a new console, carbon-13 optimized cryoprobe and tunable broadband probe for a 600 MHz NMR system, as well as a tunable broadband probe for a 500 MHz NMR spectrometer. The instrumentation will be used for studies of 1) solvent effects in cages, 2) carbon-rich networks and materials based on phenyl-acetylene scaffolding, 3) RNA structural biology, 4) development of carbon-boron-nitrogen heterocycles as hydrogen storage materials and 5)polymetal nanoclusters and Main Group supramolecular chemistry.Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organic/inorganic chemistry, biochemistry and the environment. These instruments will be an integral part of teaching as well as research.