CONFERENCE: 2011 CSHL Conference on Eularyotic mRNA Processing to be held August 23-27, 2011 in Cold Springs Harbor, NY

2011年CSHL真核mRNA加工会议将于2011年8月23-27日在纽约举行。 与前几次会议一样，主要重点将放在mRNA成熟的核事件上，特别是mRNA剪接和多聚腺苷酸化，但范围现在将扩大到包括mRNA的历史对其最终生物命运的影响，RNA干扰和microRNA功能的新兴领域以及信息学和全基因组方法在RNA加工分析中的应用。它将涵盖广泛的研究领域，包括遗传学，基因组学，生物化学，分子生物学和生物物理方法，以了解许多处理步骤的机制和生理后果，这些步骤可以影响新生的前mRNA转录物以控制基因表达。会议形式将包括八次全体会议和两次海报会议。2011年会议的每次全体会议将分为两个部分，分别讨论相关但不同的专题。 最近一次会议于2009年8月举行，吸引了335名国际科学家，他们正在积极研究真核细胞中信使RNA成熟的各个方面，使用遗传，生物化学，分子和细胞生物学方法。2011年CSHL真核mRNA加工会议将汇集一批高度多样化的科学家，寻求分享和促进该领域的知识，并为合作和交流思想提供一个出口。 2011年CSHL会议委员会已尽一切努力，包括在科学代表性不足的群体的参与。

Intellectual Merit The 2011 CSHL Conference on Eukaryotic mRNA Processing will be held in New York, August 23-27, 2011. As in the previous meetings, a major focus will be on nuclear events in mRNA maturation, particularly mRNA splicing and polyadenylation, but the scope will now be expanded to encompass both the impact of the history of an mRNA on its ultimate biological fate, the emerging fields of RNA interference and microRNA function as well as the application of informatics and genome-wide approaches to the analysis of RNA processing. It will span a broad range of areas of investigation including genetics, genomics, biochemistry, molecular biology and biophysical approaches to understand the mechanisms and physiologic consequences of the many processing steps that can impinge on a nascent pre-mRNA transcript to control gene expression. The meeting format will consist of eight plenary sessions and two poster sessions. For the 2011 meeting, each plenary session will be subdivided into two parts that focus on related but separate topics. The most recent meeting was held in August 2009 and attracted 335 scientists internationally, who are actively investigating various aspects of messenger RNA maturation in eukaryotic cells, using genetic, biochemical, molecular, and cell biological approaches. Broader Impacts The 2011 CSHL Conference on Eukaryotic mRNA Processing will bring together a highly diverse group of scientists seeking to share and promote knowledge in the field and provide an outlet for collaboration and exchange of ideas. The 2011 CSHL conference committee has made every effort to include the participation of groups underrepresented in science.