MRI: Acquisition of a 400-MHz NMR Spectrometer for Research and Teaching

有了这项来自主要研究仪器计划的奖项，西弗吉尼亚大学的Terry Gullion教授和同事Kung Wang，Bjorn Soderberg，Xiaodong Shi和Brian Popp将获得一台400 MHz的NMR光谱仪，以取代两台270 MHz的仪器。该提案旨在加强各级的研究、培训和教育，特别是在支持有机化学和催化的许多领域，如（a）扩大有机金属催化工具箱;（B）开发合成含氮杂环和碳环化合物的合成反应;（c）过渡金属催化的硝基芳族化合物的还原环化;（d）开发有机金属催化剂;（e）开发有机金属催化剂。（d）硝基芳族化合物的碱或光化学促进的环化反应;（e）α，β-不饱和Fischer卡宾络合物的成环反应;（f）官能化1，2，3-三唑的合成方法;（g）非平面多环芳烃的分子结构。核磁共振（NMR）光谱是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，并研究溶液中分子之间相互作用的动力学。对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的。这些NMR研究的结果将对合成有机/无机化学、材料化学和生物化学产生影响。该仪器将成为西弗吉尼亚大学和邻近机构教学和研究的一个组成部分。

With this award from the Major Research Instrumentation Program, Professor Terry Gullion from West Virginia University and colleagues Kung Wang, Bjorn Soderberg, Xiaodong Shi and Brian Popp will acquire a 400 MHz NMR spectrometer that would replace two 270 MHz instruments that are over 20 years old. The proposal is aimed at enhancing research training and education at all levels, especially in many areas that support organic chemistry and catalysis such as (a) expanding the organometallic catalysis toolbox; (b) development of synthetic reactions affording nitrogen-containing heterocycles and carbocyclic compounds; (c) transition metal catalyzed reductive cyclization of nitroaromatic compounds; (d) base or photochemically promoted cyclizations of nitroaromatic compounds; (e) annulation reactions of alpha,beta-unsaturated Fischer carbene complexes; (f) synthetic methods for functional 1,2,3-triazoles; and (g) molecular architectures of nonplanar polycyclic aromatic.Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organic/inorganic chemistry, materials chemistry and biochemistry. This instrument will be an integral part of teaching as well as research at West Virginia University and neighboring institutions.