MRI: Acquisition of a 500 MHz Nuclear Magnetic Resonance (NMR) Spectrometer

该奖项由主要研究仪器和化学研究仪器计划支持。来自加州圣巴巴拉大学（UCSB）的张黎明教授和他的同事布鲁斯·利普舒茨、特雷弗·海顿和哈维尔·里德·德·阿拉尼兹获得了一台500 MHz的核磁共振光谱仪，该光谱仪配备了液氮冷却探头和具有多核能力的探头。该光谱仪可用于各种领域的研究，例如加速具有重要经济意义的化学反应的研究，以及促进生物相关物种研究的研究。一般来说，核磁共振（NMR）光谱是化学家用来描述分子结构的最有力的工具之一。NMR用于识别未知物质，表征分子内原子的特定排列，并研究溶液或固态分子之间相互作用的动力学。对于从事前沿研究的化学家来说，使用最先进的NMR光谱仪是必不可少的。相对于标准NMR探针，低温探针提供了灵敏度的显著增加，而多核探针允许研究超出常见氢和碳原子的广泛元素。NMR研究提高了对合成有机/无机化学，材料化学和生物化学的理解。该仪器是教学和研究的一个组成部分。这种广泛使用的仪器加强了区域仪器基础设施，并有助于推动超过18个研究小组的约200名普通本科生和研究生研究人员，博士后和访问学者的科学事业。光谱仪丰富了教育和培训经验的代表性不足的本科生在几个NSF支持的科学，技术，工程和数学（STEM）计划和数百名本科生在化学和生物化学实验室类在UCSB和圣巴巴拉社区学院。这款核磁共振仪器也促进了当地几家专注于清洁能源和食品保存的初创公司的研发工作。授予带有冷冻探针的核磁共振光谱仪旨在加强各级研究和教育。这一收购特别有利于纳米团簇形成的热化学模型的发展和锕系元素电子结构的探索。该仪器还为研究氟化功能聚合物和在硼催化的肽键形成中使用硼-11同位素的研究人员提供服务。该奖项反映了NSF的法定使命，并通过使用基金会的知识价值和更广泛的影响审查标准进行评估，被认为值得支持。

This award is supported by the Major Research Instrumentation and the Chemistry Research Instrumentation Programs. Professor Liming Zhang from the University of California Santa Barbara (UCSB) and colleagues Bruce Lipshutz, Trevor Hayton and Javier Read de Alaniz have acquired a 500 MHz NMR spectrometer equipped with a liquid-nitrogen cooled probe and a probe with multinuclear capabilities. This spectrometer allows research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as those that facilitate studies of biologically relevant species. In general, Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists to describe the structure of molecules. NMR is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The cryogenic probe provides a significant increase in sensitivity relative to standard NMR probes while the multinuclear probe allows study of a wide range of elements above and beyond the common hydrogen and carbon atoms. The NMR studies improve understanding of synthetic organic/inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research. This broadly accessible instrumentation strengthens the regional instrumentation infrastructure and helps advance the scientific careers of about 200 regular undergraduate and graduate researchers, postdocs and visiting scholars in more than 18 research groups. The spectrometer enriches the education and training experience of underrepresented undergraduate students in several NSF-supported science, technology, engineering and mathematics (STEM) programs and several hundred undergraduate students in chemistry and biochemistry laboratory classes at UCSB and from Santa Barbara Community College. This NMR instrumentation also facilitates research and development (R&D) efforts of several local startup companies specializing in clean energy and food preservation.The award of the NMR spectrometer with a cryoprobe is aimed at enhancing research and education at all levels. This acquisition especially benefits the development of a thermochemical model for nanocluster formation and the exploration of actinide electronic structures. The instrumentation also serves researchers studying fluorinated functional polymers and those using boron-11 isotopes in boron-catalyzed peptide bond formation. Finally, the spectrometer benefits the syntheses and characterization of complex bioactive natural products.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.