A new biomechanical analyzing system based on the three-dimensional bone-implant interface structure around the implant.

本研究的目的是阐明体内种植体周围的三维骨骼结构，并开发一种新的生物力学分析系统。作者以FLOW的方式开展了这项研究。将3颗羟基磷灰石涂层种植体(“种植体”)植入3只雌性成年猴下颌无牙区，在种植前3个月摘除P2M1、M1P2、P1P2。3个月后处死猴子，摘除下颌骨。将含有种植体的组织块包埋在聚酯树脂中。这块砖每75亩米由磨床沿颊舌方向连续研磨。每个块的连续表面都放在Profile投影仪上，并追踪种植体周围的骨结构。这些数字化的数据是用个人计算机计算的。种植体周围骨的三维结构由计算机图形学完成。定量分析种植体表面0~75、75~150、150~225、225~300微米范围内的骨结构，包括骨接触率(BCR)和骨体积比(BVR)。从种植体表面铺设各区域的骨性面积，生成骨结构的模拟图像。种植体周向BCR分别为80.9%、68.1%、68.8%，BVR为60~70%。模拟图像显示了三维骨骼结构。这些结果为骨-种植体界面的研究提供了更详细的信息，为开发新的生物力学分析系统提供了可能。

The purpose of this study was to clarify the three-dimensional bone structure around the implant in vivo and to develop a new biomechanical analyzing system. The authors carried out this study as flows. Three hydroxyapatite-coated dental implants ( "Implant" ) were inserted into the mandibular edentulous areas of 3 female adult monkeys where P_2M_1, M_1P_2, P_1P_2 were removed 3 months before insertion. After 3 months, the monkeys were sacrificed and the mandibles were removed. Tissue block containing the implant was enbedded in polyester resin. This block was ground every 75 mu m serially in buccolingual direction by a grinding machine. Each serial surface of the block was put on the profile projector and the structure of the bone around the implant was traced. These digitized data were calculated with a personal computer. A three-dimensional structure of bone around the implant was completed by computer graphics. The bone structure was analyzed quantitatively, as bone contact ratio (BCR) and bone volume ratio (BVR) in each region of 0-75, 75-150, 150-225, 225-300 mu m from implant surface. Simulated images of bone structure were also produced by laying bony area of each region from implant surface. BCR around the whole implant surfaces were 80.9, 68.1, 68.8%, and BVR were 60-70% in all regions. Simulated images revealed three-dimensional bone structure. These results provide more detailed informations on bone-implant interface and a possibility to develop new biomechanical analyzing system.