The control of gastrointestinal motility in the chichen by the nutrients

研究了中链三酰甘油(MCT)延缓鸡体内作物排空率的机理。测定MCT给药途径的影响。口服或腹腔注射生理盐水、MCT或长链三酰甘油(LCT)后，测量作物排空率。与其他处理相比，只有口服MCT可以延缓作物的排空。研究了碱处理对MCT诱导的作物延迟倒空的影响，以阐明酸度的影响。碱化处理没有提高作物的排空率，最高碱化处理进一步延缓了作物的排空率。对多巴胺能或交感神经元的参与进行了研究。多巴胺能参与的作用可以忽略不计，但交感神经元的阻断进一步推迟了作物的排空。研究胆碱能机制的作用。迷走神经切断改变了给予LCT的雏鸡的作物排空，但不改变给予MCT的雏鸡的作物排空。脑网的去神经和胃的侧方连结进一步抑制了MCT诱导的食物通道。给予西沙必利和阿托品，两者都延迟了给予中链三酰甘油的雏鸡的作物排空。这些结果表明，胆碱能因子不参与含有MCT的食物从雏鸡体内延迟向前移动。研究了自发性一氧化氮释放剂硝普钠(SNP)对接受MCT雏鸡作物内容物前向传递的影响。作物的排空率随着饲料中SNP的增加而显著延迟。

The mechanism by which medium chain triacylglycerol (MCT) delayd the crop emptying rate in the chicken was investigated. The effect of administration route of MCT was determined. After oral or intraperitoneal administration of saline, MCT or long chain triacylglycerol (LCT), the crop emptying rate was measured. Only oral administration of MCT delayd the crop emptying compared with other treatments. The influence of alkaline treatment on the delayd crop emptying induced by MCT was investigated to clarify the involvement of acidity. The alkaline treatment did not improve the crop emptying and the highest treatment of alkaline further delayd the crop emptying rate. The involvement of dopaminergic or sympathetic neuron was invesetigated. The involvement of dopaminergic action was negligible, but the block of sympathetic neuron further delayd the crop emptying. The role of cholinergic mechanisms was investigated. Vagotomy altered the crop emptying of chicks given LCT,but did not alter it in chicks given MCT.Denervation in the cranial rete and lateral commisure of the gizzard further inhibited the food passage induced by MCT.Administration of cisapride, which induces acetylcholine release from the myenteric nerves, and atropine, a muscarinic cholinergic antagonist, both delayd crop emptying of chicks given medium chain triacylglycerol. These results demonstrate that cholinergic factors are not involved in the delayd forward movement of the food containing MCT from the crop of chicks. The effect of sodium nitroprusside (SNP), a spontaneous nitric oxide releaser, on the forward passage of the crop contents of chicks receiving MCT was studied. Crop emptying rate was significantly delayd as dietary SNP increased.