Mechanistic Studies of Dimethylsulfide Dehydrogenase: A Novel Bacterial Molybdoenzyme
Mechanistic Studies of Dimethylsulfide Dehydrogenase: A Novel Bacterial Molybdoenzyme
批准号:
DP0343405
负责人:
Prof Paul Bernhardt
金额:
$18.17万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2003
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2003-01-01 至 2006-12-31
中文摘要
该提案的目的是利用电化学、光谱和分子生物学技术来了解二甲硫醚脱氢酶的作用机制。这种酶代表了在微生物生物转化中具有重要性的一组主要的含氘酶。该项目将提供有关多氧化还原中心蛋白质的基本信息,该蛋白质在生物传感器和生物催化中具有潜在的应用。
英文摘要
The aim of this proposal is to use electrochemical, spectroscopic and molecular biological techniques to understand the mechanism of action of the enzyme dimethylsulfide dehydrogenase. This enzyme is representative of an major group of molybdenum-containing enzymes that have importance in microbial biotransformations. The project will provide fundamental information about a multi-redox centre protein that has potential application in biosensors and biocatalysis.
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