Ultrasonic Estimation of Bladder Weight in Men with Infravesical Obstruction

本研究的目的是开发一种敏感的非侵入性方法来检测膀胱下梗阻。一种测量膀胱重量的新方法最初是作为膀胱肥大的测量而开发的。使用7.5MHz经腹探头，根据膀胱壁的厚度计算超声估计的膀胱重量（UEBW），假设为球形膀胱。在实验研究中，10具尸体膀胱的实际膀胱重量与计算的UEBW之间存在统计学显著相关性。在临床研究中，计算了104名男性（50至89岁，平均年龄69岁）的UEBW。有膀胱下梗阻者UEBW明显高于无膀胱下梗阻者，5例BPH患者术后UEBW降至正常对照水平。在这项研究中，UEBW和压力流研究进行了65名男性（45至89岁，平均年龄71）与泌尿系统症状和UEBW预测膀胱下梗阻的能力进行了测试。因此，截止值为35 gm。UBEW对膀胱下梗阻的诊断准确率为86.2%，UBEW与Abrams-Griffiths数、尿道阻力因子和梗阻的Schafer分级有显著相关性。据推测，UEBW是一个可靠的预测膀胱下梗阻，是特别有用的监测治疗效果的男性泌尿系症状引起的膀胱下梗阻。

The aim of the present study was to develop a noninvasise method sensitive to detect infravesical obstruction. A new method for the measurement of bladder weight was originally developed as a measure of bladder hypertrophy. Using a 7.5MHz transabdominal probe, ultrasonically estimated bladder Weight (UEBW) was calculated from the thickness of the bladder wall, assuming a spheric bladder. In the experimental study there was a statistically significant correlation between the actual bladder weight of 10 cadaver bladders and the UEBW calculated. In the clinical study UEBW was calculated in 104 men (50 to 89 years old, average age 69). The UEBW was signinificantly greater in men with infravesical obstruction than that in men without it. Additionally, the high UEBW in 5 patients with BPH decreased to a nomal control level after operation. In this study, UEBW and pressure flow studies were performed in 65 men (45 to 89 years old, average age 71) with urinary symptoms and the ability of UEBW to predict infravesical obstruction was tested. As a result, a cutoff value of 35gm. for UBEW revealed a diagnostic accuracy of 86.2% for infravesical obstruction and the UEBW correlated significantly with the Abrams-Griffiths number, urethral resistance factor and the schafer grade of obstruction. It was presumed that UEBW is promising as a reliable predictor of infravesical obstruction and is particularly useful for monitoring therapeutic effects in men with urinary symptoms caused by infavesical obstruction.