2022 Mammary Gland Biology GRC and GRS

项目总结 戈登乳腺生物学研究会议(GRC MGB)和非常成功的戈登 伴随这次会议的研究研讨会(GRS)在乳腺癌会议中是独一无二的，因为 他们聚集了非常多样化的科学家和临床医生--对分子和细胞感兴趣的科学家 调控正常乳腺发育、正常生理、肿瘤发生和发展的机制 进展和转移。高度重视乳腺癌的预防和治疗(基于 阐明导致乳腺癌发生和发展的早期和晚期事件)和出现 与该领域相关的“尖端”科学。乳腺生物学GRC/GRS是唯一一个 重点了解人类乳腺和乳腺的正常生物学和发育 模型系统及其与肿瘤发生的关系，以了解导致乳腺癌和 已经成为乳腺生物学家和癌症研究人员必须参加的活动(特别是在基础 和翻译研究领域)。 我们的目标是1)坚持MGB GRC的传统，为现有的和新的专家提供展示的平台 新的科学发现和新的想法；2)促进现有研究人员与受训人员之间的讨论 在非正式会议期间，由现任领导人培训下一代，并促进导师关系。 为了实现目标1，我们组织了一个包括国际专家在内的方案，以解决广泛的 基本科学问题，谁将在会谈和海报中展示他们最新的未发表的发现 会话。会议计划将包括从摘要中挑选的简短演讲，为 初级调查员和实习生的出色工作。每次口试后都会安排充足的提问时间。 介绍，以进一步鼓励讨论。会谈后的讨论，在海报会议期间，以及更多 在用餐和下午的非正式活动中，将刺激乳腺、乳房生物学、 和乳腺癌领域。对这些新发现和创新的陈述和讨论将有助于 加深对乳腺癌发生、发展和转移的认识，为 开发更多的工具，在临床上解决这种异质性疾病。此外，通过将不同的 聚集科学家解决连接乳腺癌、预防和风险的新出现的科学问题 因素、哺乳期和乳房发展区，本次会议将营造出别开生面的创意氛围 这刺激了创新思维和合作，并每年都为重要的进展做出贡献。 为实现目标2，有机会参加“动力小时”和非正式的“与专家共进午餐”会议 “树下讨论”，实习生和高级调查人员会面，讨论科学，以及 在机遇和挑战并存的背景下，职业发展将提升下一步的发展 一代乳腺/乳腺癌生物学家。

PROJECT SUMMARY The Gordon Research Conference on Mammary Gland Biology (GRC MGB) and the highly successful Gordon Research Seminar (GRS) that accompanies this meeting are unique amongst breast cancer conferences as they bring together a very diverse mix of scientists and clinician-scientists interested in the molecular and cellular mechanisms that govern normal mammary gland development, normal physiology, tumor initiation and progression and metastasis. There is a strong focus on breast cancer prevention and treatment (based on elucidating the early and later events that contribute to breast cancer onset and progression) and emerging `cutting edge' science relevant to the field. The Mammary Gland Biology GRC/GRS is the only conference that focuses on understanding the normal biology and development of the human breast and the mammary gland in model systems, and their relationship to tumorigenesis to understand events that give rise to breast cancer and has become a `must attend' event for mammary gland biologists and cancer researchers (particularly in basic and translational research areas). We aim to 1) uphold the MGB GRC tradition of providing a platform for established and new experts to present new scientific findings and novel ideas; 2) stimulate discussions between established investigators with trainees during informal sessions to train the next generation by its current leaders and promote mentorship. To fulfil Aim 1, we have organized a program including international experts to address a wide range of fundamental scientific issues, who will present their latest unpublished findings during the talks and during poster sessions. The conference program will include short talks selected from abstracts, providing opportunities for outstanding work by junior investigators and trainees. Plentiful time will be assigned for questions after each oral presentation to further encourage discussion. Discussions after the talks, during poster sessions, and more informally during meals and afternoons will stimulate forward thinking in both the mammary gland, breast biology, and breast cancer fields. Presentations and discussions of these new findings and innovations will contribute to deepen our understanding of breast cancer initiation, progression and metastasis and will provide the basis to develop further tools to tackle this heterogenous disease in the clinic. In addition, by bringing together a diverse collection of scientists to address emerging scientific problems bridging the breast cancer, prevention and risk factors, lactation and mammary development areas, this meeting will generate a unique and creative atmosphere that spurs innovative thinking and collaborations and contributes to important advances each year. To fulfil Aim 2, opportunities to attend the “Power Hour” and informal "Lunch with the Expert" sessions and “Under the tree discussions” where trainees and senior investigators meet to meet, discuss science, as well as opportunities and challenges in the context of career development, will enhance the development of the next generation of mammary gland/breast cancer biologists.