Research Training in Global Non-Communicable Diseases

项目摘要 非传染性疾病占全球所有死亡人数的71%。然而，研究的培训机会， 全球心血管、心脏代谢、肺和血液系统疾病有限。关键问题 包括了解最佳治疗和实施方案，以改善健康和减少疾病， 人群在病理生物学和治疗反应方面的主要差异，以及相关的环境和 社会行为因素在全球范围内影响疾病进展。在这个提案中开发的程序， 全球非传染性疾病研究培训，旨在提供博士后研究员在 马萨诸塞州总医院（MGH）有出色的机会获得研究技能和高- 高质量的指导，为全球心血管，心脏代谢， 肺部和血液系统疾病。培训方案中研究员的主要活动包括： 临床有效性（明确为博士后医生设计的严格夏季计划）和其他 在哈佛T.H.的全球健康相关课程。公共卫生学院。我们还将指示 全球卫生研究实施和管理以及职业发展方面的研究员， 基于程序的研讨会和课程在临床研究的MGH部门。额外的专业 开发资源将通过多个基于MGH的倡议和哈佛催化剂提供。的 拟议的计划还将支持一个实践社区，以促进研究员之间的联系， 导师和其他全球健康研究人员的专业发展和健康。另夕h 一批忠诚和有才华的导师将接受高级导师培训 以最大限度地提高支持研究员的效率。重要的是，该计划将努力实现多样性 并促进全球卫生伙伴关系中的公平。我们的目标如下： 1.在心血管和心脏代谢的高影响力全球健康研究中提供指导研究， 肺和血液疾病，以培养下一代全球健康调查人员 2.通过课程和研讨会进行研究培训，通过社区的 全球卫生调查员的实践模式 3.培训导师，以优化在全球卫生研究中工作的受支持学员的成功。 全球非传染性疾病研究培训计划将为总共8名研究员提供支持 (two每年），每个人都接受两年的研究支持，教学培训， 研究和职业指导。该计划旨在为所有研究员的研究生涯做好准备，包括 职业发展和过渡到独立的NIH资助的研究。该计划的影响将是 通过指导的质量以及研究员的生产力和进步来衡量。

PROJECT SUMMARY Non-communicable diseases account for 71% of all deaths globally. Yet, training opportunities for research in global cardiovascular, cardiometabolic, pulmonary, and hematologic diseases are limited. Critical questions involve understanding optimal treatment and implementation programs to improve health and reduce disease, key differences among populations in pathobiology and treatment responses, and relevant environmental and socio-behavioral factors that influence disease progression globally. The program developed in this proposal, Research Training in Global Non-Communicable Diseases, is designed to provide post-doctoral fellows at Massachusetts General Hospital (MGH) with outstanding opportunities to obtain research skills and high- quality mentorship to prepare for research careers addressing global cardiovascular, cardiometabolic, pulmonary, and hematologic diseases. Key activities for fellows in the training program include the Program in Clinical Effectiveness (a rigorous summer program designed explicitly for postdoctoral physicians) and other coursework relevant for global health at the Harvard T.H. Chan School of Public Health. We will also instruct fellows on global health research implementation and administration as well as career development through program-based seminars and courses in the MGH Division of Clinical Research. Additional professional development resources will be available through multiple MGH-based initiatives and the Harvard Catalyst. The proposed program will also support a Community of Practice to promote connections among the fellows, their mentors, and other global health researchers for professional development and wellness. Additionally, the committed and talented group of mentors available to the fellows will receive advanced training in mentorship to optimize the effectiveness in supporting the fellows. Importantly, the program will strive for diversity among its fellows and promote equity within global health partnerships. Our aims are as follows: 1. Provide mentored research in high-impact global health research of cardiovascular and cardiometabolic, pulmonary, and hematologic diseases to develop the next generation of global health investigators 2. Conduct research training through coursework and seminars that is enriched through a Community of Practice model among global health investigators 3. Train mentors to optimize the success of supported trainees working in global health research. The Research Training in Global Non-Communicable Diseases Program will support a total of eight fellows (two per year), each receiving two years of research support, didactic training, and intense and purposeful research and career mentorship. The program aims to prepare all fellows for research careers, including career development and transition to independent NIH-funded research. Impact of the program will be measured through the quality of mentorship, as well as the productivity and advancement of the fellows.