LOW BIRTH WEIGHT ACROSS GENERATIONS

关于婴儿出生体重之间相关性的原始描述 母亲和她们的婴儿之后是对 产妇出生体重过大与分娩的关系 巨型婴儿(重4000克)。其他胎儿生长参数的研究， 包括身长和头围，表明低出生体型的婴儿 与出生体重较大的婴儿相比，母亲的出生体重更矮、更轻。 母亲，但婴儿的比例正常。 在随后的研究中，田纳西州出生的婴儿的出生证明 在1979至1984年间，与他们的母亲匹配，后者是 1959年至1966年出生于田纳西州。母婴分娩 权重再次被证明是相关的。此外，那些曾经是 低出生体重的人有高达4倍的可能性 小于胎龄的婴儿和体重在4000-4499之间的女性 出生时体重为10克，但低出生体重女性的可能性不到两倍 生一个早产儿。一群瑞典妇女，出生于1955年至 1965年，是下一个研究对象。那些对怀孕来说个子很小的女人 出生年龄增加了生育这两个孩子的风险 小于胎龄儿和早产儿。早产的妇女 出生时发生这两种结果的风险都不会增加。 1960年出生的女孩S作为研究对象的数据分析 合作围产期项目和丹麦围产期研究是 目前正在进行，以检查它们的生育史。 已找到小于胎龄、早产和对照女孩 并接受了采访。他们分娩的医院记录也是 已取回。

The original description of the correlation between birthweights of mothers and their infants was followed by the description of the association between large maternal birth weight and delivery of a macrosomic (>4000 gram) infant. Study of other fetal growth parameters, including length and head circumference, demonstrated that infants of low birth weight mothers were both shorter and lighter than infants of larger mothers, but that the infants were normally proportioned. In ensuing studies, birth certificates of infants born in Tennessee between 1979 to 1984 were matched with those of their mothers, who were born in Tennessee between 1959 to 1966. Maternal and infant birth weights were again shown to be correlated. In addition, women who were themselves of low birth weight were up to 4 times as likely to have a small-for-gestational age infant as were women who weighed 4000-4499 grams at birth, but low birth weight women were less than twice as likely to have a preterm infant. A group of Swedish women, born from 1955 to 1965, was next studied. Women who themselves were small-for gestational age at birth were at increased risk of giving birth to both small-for-gestational age and preterm infants. Women who were preterm at birth were not at increased risk of either outcome. Analysis of data from girls who were born in the 1960's as subjects in the Collaborative Perinatal Project and Danish Perinatal Study is currently underway in order to examine their reproductive histories. Small-for-gestational age, preterm and control girls have been located and interviewed. Hospital records of their deliveries have also been retrieved.