PORTABLE LINE SCANNING LASER OPHTHALMOSCOPE

物理科学公司(PSI)提出基于共焦扫描激光检眼镜（SLQ）的原理开发和商业化新型检眼镜。虽然共焦SLO具有许多有价值的诊断能力，但商业上可用的设备体积大，价格昂贵，并且对于现场应用是不切实际的。在拟议的第一阶段计划中，PSI将设计和演示一种扫描激光成像设备，使用更简单，可能紧凑的光学设计，现成的组件，以及比当前SLO仪器少得多的移动部件。在此基础上，将指定一个紧凑的原型的要求。在第二阶段，我们将开发和测试一个紧凑的工程原型设备，用于临床演示和商业开发。该设备将适用于各种条件下的眼底检查，包括现场和紧急医疗用途。第二阶段的原型将包括简单的心理物理检查能力，多波长和立体成像，并将可用于检查眼前节的眼睛。拟定商业应用：拟议研究的成功结果将导致改进诊断系统，用于早期检测和诊断视网膜疾病和其他视觉障碍。所提出的方法将导致一类新的廉价的临床共焦成像仪器，并增加SLO相关设备的适用性和商业价值。

Physical Sciences Inc. (PSI) proposes to develop and commercialize a new type of ophthalmoscope based upon the principles of the confocal Scanning Laser Ophthalmoscope (SLQ). Though the confocal SLO has many valuable diagnostic capabilities, commercially available devices are large, expensive and are impractical for field applications. In the proposed Phase l program, PSI will design and demonstrate a scanning laser imaging device, using a simpler, potentially compact optical design, off-the-shelf components, and many fewer moving parts than current SLO instruments. Based on this work, the requirements for a compact prototype will be specified. In Phase II, we will develop and test a compact engineering prototype device for clinical demonstration and commercial development. This device will be suitable for fundus examination under a wide variety of conditions, including field and emergency medical uses. The Phase II prototype will incorporate simple psychophysical examination capabilities, multi-wavelength and stereoscopic imaging, and will be useable for examination of the anterior segment of the eye. PROPOSED COMMERCIAL APPLICATION: The successful outcome of the proposed research would lead to improved diagnostic systems for the early detection and diagnosis of retinal disease and other visual disorders. The proposed approach will result in a new class of inexpensive, clinical confocal imaging instruments, and increase the applicability and commercial value of SLO-related devices.