Designing the most effective vehicle to deliver alginate to effectively reduce fat digestion and absorption

肥胖是世界上增长最快的医疗问题之一，也正在迅速成为导致死亡的主要原因之一。在英国，每年33.7万人的死亡与超重有关，而英国在与超重有关的死亡人数中居欧盟首位。肥胖将成为欧盟未来的一个更严重的问题，因为2200万儿童被认为超重或肥胖，这一数字每年增加40万。在我们之前由BBSRC资助的研究中，我们证明了海藻酸盐(来自海藻的膳食纤维)可以减少脂肪的消化和吸收，因此可以帮助减少肥胖。我们与Gregg的PLC一起开发了一种基于面包的海藻酸盐产品，该产品可被高度接受，没有肠道相关的副作用。在这里，我们打算通过咨询公众的意见来开发一系列以藻酸盐为基础的食品，并进行进一步的研究，使我们能够提出健康声明。这将为藻酸盐产品作为减肥辅助产品进入市场铺平道路。

Obesity is one of the fastest growing medical issues across the world and is fast becoming one of the leading causes of mortality. 337,000 death/year in Britain are related to being overweight and Britain leads EU in deaths related to excess body weight. Obesity will become an even greater problem in the future for the EU as 22 million children are considered overweight or obese, with this increasing by 400,000 every year. In our previous studies funded by BBSRC we demonstrated that alginates (dietary fibres from seaweeds) could reduce fat digestion and absorption, so could help to reduce obesity. We along with Gregg's PLC have developed a bread based alginate product which was highly acceptable with no bowel related side effects. Here we intend to develop a range of alginate based food products driven by consultation with the public and carry out further studies to allow us to make a health claim. This will pave the way for alginate products to come to market as an aid to weight loss.