Genome-wide discovery of translation control mechanisms

该项目旨在揭示目前未知的蛋白质合成的分子细节，这是基因表达的一个步骤，对所有生命都至关重要。为了实现这一目标，基于下一代测序的创新方法将在酵母模型生物中部署。酵母作为病原体在食品和生物技术工业领域都具有重要意义。因此，该项目产生的新知识将有助于解决侵入性致病行为和生物量生产问题。

This project aims to reveal currently unknown molecular details of protein synthesis, a step of gene expression that is central to all of life. To achieve this, innovative methods based on next-generation sequencing will be deployed in the yeast model organism. Yeasts are of importance as pathogens as well as in the food and biotechnology industry sector. Thus, new knowledge generated in this project will help solve problems of invasive pathogenic behaviour and biomass production.