AUDITORY EVOKED BRAIN POTENTIALS IN NEUROLOGICAL DISEASE

我们计划在两个临床神经学领域研究听觉诱发电位 疾病和动物实验以确定神经机制 这些潜能的产生。特别是，我们将在 实验动物脑桥听觉结构在发育过程中的作用 使用离散病变方法的听觉脑干组件。这个 生成中延迟、长延迟和内源性组件将 使用电记录和损伤方法对猴子进行检查 从事一项听觉辨别任务。浅谈听觉功能的应用 神经功能障碍患者的诱发电位将用于1) 昏迷恢复过程中的时间和内源性成分；2) 任务复杂性对痴呆患者内源性成分的影响 3)患者词汇化过程中的内源性成分 患有失语症。

We plan to study auditory evoked potentials in both clinical neurological disorders and animal experiments to define neural mechanisms of the generation of these potentials. In particular, we will study in experimental animals the role of pontine auditory structures in generating auditory brainstem components using discrete lesion methods. The generation of middle-latency, long-latency, and endogenous components will be examined using electrical recording and lesion methods in monkeys engaged in an auditory discrimination task. The application of auditory evoked potentials to patients with neurological disorders will be for 1) longlatency and endogenous components during the recovery from coma; 2) the effects of task complexity on endogenous components in dementing illnesses and 3) endogenous components during the catagorization of words in patients with aphasia.