CONFERENCE ON MOLECULAR NEUROBIOLOGY

本次加州大学洛杉矶分校研讨会将解决分子神经生物学与特别 强调癌基因和生长因子在神经生物学中的作用。 在分子肿瘤学， 逆转录病毒学，无脊椎动物遗传学，转录调控和 发育生物学通过异花受精的过程， 更好地理解一些神经元的分子机制， 细胞功能 例如，基因调控长期以来被认为是一种 神经发育和神经生理学的关键方面;然而， 癌基因和转录因子探针和技术的可用性 直到最近才促进了对特定基因表达的直接分析， 神经系统 此外，癌基因产物产生重要的 深入了解信号通路，也用于逆转录病毒 载体和转基因小鼠来研究神经发育。 的共性 这些方法是应用现代分子生物学技术， 神经科学 这些技术是跨学科的，它们不 认识到系统发育的界限。 因此，他们联合起来，例如， 果蝇遗传学，失智行为，电生理，转基因小鼠 以及脊椎动物中的DNA-蛋白质相互作用。 这次会议的目的是 将不同领域的科学家聚集在一起， 相互作用，可以帮助定义分子生物学方法， 了解神经系统的生理学。

This UCLA Symposium will address Molecular Neurobiology with particular emphasis on the role of oncogenes and growth factors in neurobiology. Breakthroughs in such diverse disciplines as molecular oncology, retrovirology, invertebrate genetics, transcriptional regulation and developmental biology have led, by a process of cross-fertilization, to a better understanding of some molecular mechanisms that underlie neuronal cell function. For instance, gene regulation has long been recognized as a critical aspect of neurodevelopment and neurophysiology; however, availability of oncogene and transcription factor probes and technology has only recently facilitated a direct analysis of specific gene expression in the nervous system. Additionally, oncogene products have yield vital insights into signaling pathways and have also been used in retrovirus vectors and transgenic mice to study neurodevelopment. The commonality of these approaches is application of modern molecular biology technology to the neurosciences. Such techniques are interdisciplinary and they do not recognize phylogenetic boundaries. Therefore, they unite, for example, Drosophila genetics, Aplysia behavior, electrophysiology, transgeneic mice and DNA-protein interactions in vertebrates. The goal of this meeting is to bring together scientists form these different areas to promote interactions that can help to define the molecular biological approaches to understanding the physiology of the nervous system.