FACTORS DETERMINING MAXIMAL EXERCISE PERFORMANCE IN MAN

我们最近在184名非耐力训练的非肥胖男性中证明， 和来自巴尔的摩老龄化纵向研究（BLSA）的女性， 最大运动心电图显示，年龄相关的最大氧含量下降 最大摄氧量（VO.max）恢复正常后明显降低 而不是体重。 这些结果表明， 外周（与中心循环）因素在 与年龄相关的最大有氧运动能力下降。 一个密切相关 问题是，有充分证据证明的老年人VO，max的显著增加是否 耐力训练的男子相对于年龄匹配的同龄人是介导的 主要是通过中枢与外周的适应性。 我们进行 放射性核素心室造影术和VO，最大直立期间的测量 耐力训练的自行车测力计（平均年龄= 65 ± 5岁，踏车VO 最大摄氧量= 51 + 4 ml/kg/min）和6名年龄匹配的久坐者（跑台摄氧量最大= 31 + 4 ml/kg min）男性。

We have recently demonstrated in 184 non endurance trained non obese men and women from the Baltimore Longitudinal Study of Aging (BLSA) with normal maximal exercise ECGs that the age-associated decline in maximal oxygen consumption (VO.max) was markedly attenuated after VO.max was normalized for total muscle mass instead of body weight. These results suggested an important role of peripheral (vs central circulatory) factors in the age-related reduction of maximal aerobic performance. A closely related issue is whether the well documented marked increase in VO,max of older endurance trained men relative to that of age-matched peers is mediated primarily by central versus peripheral adaptations. We performed radionuclide ventriculography and VO, measurements during maximal upright bicycle ergometry in endurance trained (mean age = 65 + 5 yr, treadmill VO max = 51 + 4 ml/kg/min) and 6 age-matched sedentary (treadmill VO2max = 31 + 4 mi/kg min) men.