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AIDS RELATED PROTEINS--STRUCTURE AND FUNCTION

AIDS RELATED PROTEINS--STRUCTURE AND FUNCTION
艾滋病相关蛋白质——结构和功能
批准号：
3754323
负责人：
D R DAVIES
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3754323
关键词：
X ray crystallography crystallization human immunodeficiency virus 1 light scattering molecular cloning mutant protein purification protein structure function solubility virus protein

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中文摘要
翻译
HIV-1整合的几种N-和C-末端缺失突变体 蛋白质已被克隆、纯化并进行结晶 审判两种缺失形式的溶解度性质， 保留活动已得到显着改善，伴随着 光散射法测定其齐聚反应的改进 特性.
英文摘要
Several N- and C-terminal deletion mutants of the HIV-1 integration protein have been cloned, purified and subjected to crystallization trials. The solubility properties of two deletion forms which still retain the activity have been significantly improved with an accompanying improvement in the light scattering analysis of their oligomerization properties.
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