课题基金 / 基金详情

Cross-talk between cytokine and pathogen recognition receptor networks in the pathogenesis of gastric cancer

Cross-talk between cytokine and pathogen recognition receptor networks in the pathogenesis of gastric cancer
胃癌发病机制中细胞因子和病原体识别受体网络之间的串扰
批准号:
nhmrc : 490956
负责人:
A/Pr Ashley Mansell
金额:
$11.66万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2008-12-31

项目摘要

项目成果

A/Pr Ashley Mansell的其他基金

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相关文献

中文摘要
翻译
胃癌是全球与癌症相关的死亡的第二大常见原因,仅在澳大利亚每年就导致数千人死亡。我们在一种名为gp130的基因中发现了一种特殊的突变,这种突变会导致小鼠胃炎和胃癌的形成。我们现在的目标是了解这种突变导致慢性炎症和随后胃壁上皮细胞不受控制的生长的确切分子事件。
英文摘要
Stomach cancer is the second most common cause of cancer-related deaths worldwide, and results in the yearly death of several thousand people in Australia alone. We have discovered a specific mutation in a gene called gp130 that results in the formation of gastritis and stomach cancer in mice. We are now aiming to understand the exact molecular events by which this mutation results in chronic inflammation and the subsequent uncontrolled growth of epithelial cells that line the stomach wall.
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INFLAMMASOMES AND INTERLEUKIN-18 SIGNALLING: NOVEL BIOMARKERS AND THERAPEUTIC TARGETS FOR KIDNEY DISEASE
  • 批准号:
    nhmrc : GNT1143674
  • 项目类别:
    Project Grants
  • 资助金额:
    $100.33万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Ashley Mansell
  • 依托单位:
INFLAMMASOMES AND INTERLEUKIN-18 SIGNALLING: NOVEL BIOMARKERS AND THERAPEUTIC TARGETS FOR KIDNEY DISEASE
  • 批准号:
    nhmrc : 1143674
  • 项目类别:
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  • 资助金额:
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  • 财政年份:
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  • 负责人:
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Regulation of immune responses in the adult testis and male reproductive health
  • 批准号:
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  • 项目类别:
    Project Grants
  • 资助金额:
    $63.79万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Ashley Mansell
  • 依托单位:
Regulation of immune responses in the adult testis and male reproductive health
  • 批准号:
    nhmrc : 1125149
  • 项目类别:
    Project Grants
  • 资助金额:
    $43.53万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Ashley Mansell
  • 依托单位:
国内基金
海外基金
基于NLRP3炎性小体与自噬Cross-talk探讨心康冲剂干预心肌纤维化的机制研究
PKM2琥珀酰化修饰介导癌细胞与血小板间Cross-talk调控胆管癌侵袭转移的研究
  • 批准号:
    JCZRYB202500379
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
  • 依托单位:
三痹汤激活线粒体自噬影响免疫细胞Cross talk延缓椎间盘退变的机制研究